Electro and Magnetooptic Studies of Phospholipid Tubules

磷脂小管的电和磁光研究

• 批准号: 8822228
• 负责人: Charles Rosenblatt
• 金额: $ 21.56万
• 依托单位: Case Western Reserve University
• 依托单位国家: 美国
• 项目类别: Continuing Grant
• 财政年份: 1989
• 资助国家: 美国
• 起止时间: 1989-04-01 至 1992-03-31
• 项目状态: 已结题
• 来源: https://www.nsf.gov/awardsearch/showAward?AWD_ID=8822228&HistoricalAwards=false
• 关键词: Electro; Magnetooptic; Studies; Phospholipid; Tubules; Electro; Magnetooptic; Studies; Phospholipid; Tubules

Under appropriate conditions of temperature, concentration and pressure, phospholipids organize into a variety of interesting and potentially useful structures, including flat lamellae, elongated rodlike structures, and closed vesicles. These vesicles range in dimension from hundreds of angstroms to tens of microns and consist of bilayers separated by an aqueous medium. A new structure composed of a polymerizable diacetylenic phospholipid was recently discovered by a joint Naval Research Laboratory/Geo-Centers group. Below 39 C pieces of bilayer assemble into straight, hollow tubules in a form similar to a roll of aluminum foil. A number of magneto-and electrooptic experiments are planned with these materials. Cotton-Mouton measurements will be made on dilute suspensions of tubles in order to better understand the molecular orientation with the tubule. At higher concentrations, birefringence and light scattering will be used to determine the interparticle potential of tubules in suspension, both the short and long range parts. In addition, an attempt will be made to locate a liquid crystal nematic phase which, if successful, will be complemented with studies of the mechanical properties and possible non-linear optical response. Finally, a number of different studies will be made involving tubule manipulation.

在适当的温度，浓度和压力的条件下，磷脂组织成各种有趣且潜在的有用的结构，包括平坦的片状，细长的棒状棒状结构和封闭的囊泡。 这些囊泡的范围从数百个埃绳到数十微米的尺寸范围，由被水介质隔开的双层组成。 最近，联合海军研究实验室/地理中心组发现了一种由可聚合二乙酰磷脂组成的新结构。 低于39℃的双层片以类似于铝箔类似的形式组装成直的空心小管。 这些材料计划了许多磁铁和电磁实验。 棉花摩顿的测量将以稀释液的悬浮液进行，以便更好地了解用小管的分子取向。 在较高的浓度下，将使用双重散射和光散射来确定小管在悬浮液中的颗粒室内电势，包括短距离和远距离部分。 此外，将尝试定位液晶列相位，如果成功，将与机械性能的研究和可能的非线性光学响应相辅相成。 最后，将进行许多涉及小管操作的不同研究。