How do kangaroo herpesviruses jump to new host species?

袋鼠疱疹病毒如何转移到新的宿主物种？

• 批准号: DP230102121
• 负责人: Prof Joanne Devlin
• 金额: $ 26.66万
• 依托单位: The University of Melbourne
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2023
• 资助国家: 澳大利亚
• 起止时间: 2023-12-31 至 2026-12-30
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP230102121
• 关键词: How; do; kangaroo; herpesviruses; jump

This project aims to study alphaherpesviruses of kangaroos and other marsupials. These viruses cause outbreaks of severe disease in captive populations of marsupials when they are transmitted from natural hosts to new host species, but these cross-species transmission events are poorly understood. This project aims to study these viruses, and their capacity for cross-species transmission, using new approaches that consider herpesviruses as dynamic, mixed populations of viruses. This project also aims to develop novel, practical, and accessible vaccines to prevent disease. Benefits are expected to arise through prevention of disease in captive marsupial populations, including benefits for conservation efforts and for Australian tourism.

该项目旨在研究袋鼠和其他​​有袋动物的αHerpesvirus。这些病毒从天然宿主传播到新的宿主物种时会导致圈养圈中的严重疾病爆发，但是这些跨物种的传播事件知之甚少。该项目旨在使用将疱疹病毒视为动态，混合病毒的新方法来研究这些病毒及其跨物种传播的能力。该项目还旨在开发新颖，实用和可获得的疫苗以预防疾病。预计将通过预防圈养人群中的疾病，包括保护工作和澳大利亚旅游业的福利。