Electrical stimulation prior to nerve transection and surgical repair promotes nerve regeneration and functional recovery in a manner exceeding a conditioning lesion

神经横断和手术修复之前的电刺激以超过调节损伤的方式促进神经再生和功能恢复

• 批准号: 390582
• 负责人: Webber Christine A
• 金额: $ 44.58万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2018
• 资助国家: 加拿大
• 起止时间: 2018-09-01 至 2023-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=390582&lang=en
• 关键词: Clinical Feasibility; Conditioning Lesion; Electrical Stimulation; Foot Drop; Motor Nerve; Nerve Regeneration; Regeneration-Associated Genes; Sensory Nerve

Peripheral nerve injury is common, especially among young, working individuals. Unfortunately, with current treatments, nerve regeneration following severe injury is often poor. A major reason is the very slow rate of regrowth, at 0.5-1 mm/day. Through an

周围神经损伤很常见，尤其是在年轻的工作人员中。不幸的是，采用目前的治疗方法，严重损伤后的神经再生往往很差。一个主要原因是再生速度非常慢，为 0.5-1 毫米/天。通过一个