CEACAM-1 and TIM-3 interactions in HIV reservoir establishment, persistence and evasion from HIV specific immunity.

CEACAM-1 和 TIM-3 在 HIV 储存库建立、持续性和逃避 HIV 特异性免疫中的相互作用。

• 批准号: 371636
• 负责人: Ostrowski Mario A
• 金额: $ 50.16万
• 依托单位: University of Toronto
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-09-01 至 2022-09-01
• 项目状态: 已结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=371636&lang=en
• 关键词: Cd4 Cells; Ceacam-1; Ctl; Cytotoxic T Cell; Hiv; Hiv Cure Research; Immune Exhaustion; Immunotherapy; Latency; Tim-3

No therapy can yet rid the body of HIV, the virus that causes AIDS, thus requiring life-long adherence to drugs. People on effective therapy harbour residual virus in their bodies, which can remain silent or 'latent' for many years, in areas of the body c

目前还没有任何治疗方法可以清除体内的艾滋病毒（HIV），这种病毒会导致艾滋病，因此需要终生坚持药物治疗。接受有效治疗的人体内残留病毒，这些病毒可以在身体的某些部位保持沉默或“潜伏”多年。