The UK Smoke Constituents Testing Study. Summary of Results and Comparison with Other Studies

Abstract At the request of the UK Department of Health, samples of 25 commercial UK cigarette brands were provided to LGC Ltd a for smoke analysis. The brands reflected a high market share (58% in July 2001) and included a wide range of blend and product styles manufactured and imported into the UK.= 0.76), suggesting a minor role of other design features on constituents yield variability. This was confirmed by the application of multiple regression analysis to the data. A subset of five brands, retested at another laboratory, gave between-laboratory differences in mean constituent yields of as much as 2.5-fold. Consideration of these results, other likely sources of analytical variation in this study and a review of other studies, clearly indicates that any tolerance values to be associated with individual smoke constituent measurements will be greater than those for NFDPM, and in some cases, much greater. Consistent with the reported results from other large studies it is concluded that, under ISO smoking conditions, smoke constituent yields are largely predictable, if NFDPM and CO yields are known, for a standard cigarette. Given these observations and the likely limitations of analytical determination, the need for routine measurement of smoke constituent yields, other than NFDPM, nicotine or CO, on standard cigarettes, is questionable.

摘要 应英国卫生部的要求，25个英国商业香烟品牌的样本被提供给LGC有限公司进行烟雾分析。这些品牌占据较高的市场份额（2001年7月为58%），包括多种在英国生产和进口的混合型及产品样式。（相关系数为0.76），这表明其他设计特征对成分产量变异性的影响较小。对数据进行多元回归分析证实了这一点。五个品牌的一个子集在另一个实验室进行了重新测试，实验室间平均成分产量的差异高达2.5倍。考虑到这些结果、本研究中分析变异的其他可能来源以及对其他研究的回顾，明确表明与单个烟雾成分测量相关的任何公差值将大于非焦油干颗粒物（NFDPM）的公差值，在某些情况下，会大得多。与其他大型研究报告的结果一致，得出的结论是，在国际标准化组织（ISO）吸烟条件下，如果已知非焦油干颗粒物和一氧化碳的产量，对于一种标准香烟，烟雾成分产量在很大程度上是可预测的。鉴于这些观察结果以及分析测定可能存在的局限性，对于标准香烟除非焦油干颗粒物、尼古丁或一氧化碳之外的烟雾成分产量进行常规测量的必要性是值得怀疑的。