Dielectric Properties of Human Active Liver, Kidney and Spleen Compared to Those of Respective Inactive Tissues, Porcine Tissues and the Data Provided by a Database in the Frequency Range of 10 Hz to 100 MHz

Objective: The purpose of this work is to study whether the active state and species of biological tissues can influence changes in their dielectric properties. Methods: In this paper, the dielectric properties of liver, kidney and spleen tissues from human active, human inactive and animal tissues are measured in the frequency range of 10 Hz to 100 MHz. The four- and two-electrode methods are used to measure dielectric properties at different frequencies. Statistical analysis and the pattern recognition method are used to compare the dielectric properties of human active tissues, human inactive tissues, animal tissues and data provided by the IFAC database. Results: The results show that the dielectric properties of human active tissues are significantly different from those of human inactive tissues and animal tissues, resulting in a great difference between the dielectric properties provided by the IFAC database and those of human active tissues. The dielectric properties of human active tissues can be identified by the pattern recognition method based on principal component analysis, which further proves that the dielectric properties of human active tissues cannot be replaced. Conclusion: The dielectric properties of biological tissues are closely related to the activity and species of tissues. The dielectric properties of human active tissues cannot be replaced by those of human cadaver tissues or animal tissues. Significance: The significance of this study is suggesting that the IFAC database should be updated with the dielectric properties of human active tissues to provide accurate data for bioelectromagnetics research.

目的：本研究旨在探讨生物组织的活性状态和种类是否会影响其介电特性的变化。 方法：本文在10Hz至100MHz的频率范围内测量了来自人体活性状态、人体非活性状态以及动物组织的肝脏、肾脏和脾脏组织的介电特性。采用四电极法和双电极法测量不同频率下的介电特性。运用统计分析和模式识别方法比较人体活性组织、人体非活性组织、动物组织的介电特性以及国际自动控制联合会（IFAC）数据库提供的数据。 结果：结果表明，人体活性组织的介电特性与人体非活性组织和动物组织的介电特性显著不同，导致IFAC数据库提供的介电特性与人体活性组织的介电特性存在很大差异。基于主成分分析的模式识别方法能够识别人体活性组织的介电特性，这进一步证明人体活性组织的介电特性不可替代。 结论：生物组织的介电特性与组织的活性和种类密切相关。人体活性组织的介电特性不能被人体尸体组织或动物组织的介电特性所替代。 意义：本研究的意义在于建议应使用人体活性组织的介电特性对IFAC数据库进行更新，以便为生物电磁学研究提供准确的数据。