Biomanufacturing in low Earth orbit for regenerative medicine.

Research in low Earth orbit (LEO) has become more accessible. The 2020 Biomanufacturing in Space Symposium reviewed space-based regenerative medicine research and discussed leveraging LEO to advance biomanufacturing for regenerative medicine applications. The symposium identified areas where financial investments could stimulate advancements overcoming technical barriers. Opportunities in disease modeling, stem-cell-derived products, and biofabrication were highlighted. The symposium will initiate a roadmap to a sustainable market for regenerative medicine biomanufacturing in space. This perspective summarizes the 2020 Biomanufacturing in Space Symposium, highlights key biomanufacturing opportunities in LEO, and lays the framework for a roadmap to regenerative medicine biomanufacturing in space. Sharma and colleagues recap the 2020 Biomanufacturing in Space Symposium, which reviewed space-based regenerative medicine research and discussed opportunities to leverage low Earth orbit (LEO) to advance biomanufacturing for regenerative medicine. This perspective will highlight key biomanufacturing opportunities in LEO, note current technical gaps, and discuss next steps in developing a roadmap to biomanufacturing in space for regenerative medicine applications.

近地轨道（LEO）研究已变得更容易开展。2020年太空生物制造研讨会回顾了基于太空的再生医学研究，并讨论了利用近地轨道推进用于再生医学应用的生物制造。该研讨会确定了金融投资可刺激克服技术障碍取得进展的领域。疾病建模、干细胞衍生产品和生物制造方面的机遇得到了强调。该研讨会将启动太空再生医学生物制造可持续市场的路线图。本观点总结了2020年太空生物制造研讨会，强调了近地轨道的关键生物制造机遇，并为太空再生医学生物制造路线图奠定了框架。 夏尔马及其同事回顾了2020年太空生物制造研讨会，该研讨会回顾了基于太空的再生医学研究，并讨论了利用近地轨道推进再生医学生物制造的机遇。本观点将强调近地轨道的关键生物制造机遇，指出当前的技术差距，并讨论为再生医学应用制定太空生物制造路线图的后续步骤。