Estimation of population-specific values of theta for PowerPlex Y23 profiles

We examine 31,011 PPY23 profiles at the population, metapopulation and world levels. Most haplotypes appear only once but a few have higher counts, including a set of 23 matching profiles in Delhi, India and a set of 16 matching profiles in Burkina Faso with one additional matching American African profile. We estimate F S T values to be used as “theta” (θ) in match probability calculations, following the method we used in our earlier survey of autosomal STR data. Match probability estimates using F ˆ S T or the κ method of Brenner for a previously unseen profile are similar but differ for any profile previously seen.

我们在群体、集合种群和世界层面研究了31011个PPY23基因图谱。大多数单倍型只出现一次，但有少数出现次数较多，包括在印度德里的一组23个匹配图谱，以及在布基纳法索的一组16个匹配图谱，还有一个额外匹配的非裔美国人图谱。我们按照我们在早期常染色体STR数据调查中使用的方法，估算了FST值，以便在匹配概率计算中用作“θ”。对于一个之前未见过的图谱，使用FˆST或布伦纳的κ方法进行的匹配概率估算相似，但对于任何之前见过的图谱则有所不同。