Development of Advanced Fermentor Control Applications for Use in an Industrial Automation Environment

We present a software platform developed by Genentech and MathWorks Consulting Group that allows arbitrary MATLAB (MATLAB is a registered trademark of The MathWorks, Inc.) functions to perform supervisory control of process equipment (in this case, fermentors) via the OLE for process control (OPC) communication protocol, under the direction of an industrial automation layer. The software features automated synchronization and deployment of server control code and has been proven to be tolerant of OPC communication interruptions. Since deployment in the spring of 2010, this software has successfully performed supervisory control of more than 700 microbial fermentations in the Genentech pilot plant and has enabled significant reductions in the time required to develop and implement novel control strategies (months reduced to days). The software is available for download at the MathWorks File Exchange Web site athttp://www.mathworks.com/matlabcentral/fileexchange/36866.

我们介绍一个由基因泰克（Genentech）和MathWorks咨询集团开发的软件平台，该平台允许任意的MATLAB（MATLAB是The MathWorks公司的注册商标）函数在工业自动化层的指导下，通过用于过程控制的OLE（OPC）通信协议对过程设备（在此情况下为发酵罐）进行监控。该软件具有服务器控制代码的自动同步和部署功能，并且已被证明能够容忍OPC通信中断。自2010年春季部署以来，该软件已在基因泰克的中试工厂成功对700多次微生物发酵进行了监控，并大大缩短了开发和实施新型控制策略所需的时间（从数月缩短到数天）。该软件可在MathWorks文件交换网站http://www.mathworks.com/matlabcentral/fileexchange/36866下载。