Aromatic cyclic peroxides and related keto-compounds from the Plakortis sp. component of a sponge consortium.

Six unreported aromatic compounds, 1–6, were isolated, along with the known compounds dehydrocurcuphenol and manoalide, from a sample of Plakortis sp., which was the main component of a Pacific sponge consortium. The new molecules were chemically characterized by spectroscopic methods. Compounds 1–4 contain a six-membered cyclic peroxide, whereas 5 and 6 display a terminal methyl ketone. The new metabolites were tested for antifungal and antibacterial properties. Compounds 1 and 4 were weakly active against S. aureus.

从太平洋海绵聚生体的主要成分普拉孔菌属（Plakortis sp.）的一个样本中，分离出了6种未被报道的芳香族化合物1 - 6，以及已知化合物去氢姜黄酚（dehydrocurcuphenol）和马诺内酯（manoalide）。通过光谱方法对这些新分子进行了化学表征。化合物1 - 4含有一个六元环过氧化物，而5和6具有一个末端甲基酮。对这些新的代谢物进行了抗真菌和抗菌性能测试。化合物1和4对金黄色葡萄球菌有微弱的活性。