A randomized trial of a behavioral intervention for high risk substance-using MSM.

Substance-using men who have sex with men (MSM) are among the groups at highest risk for HIV infection in the United States. We report the results of a randomized trial testing the efficacy of a small group sexual and substance use risk reduction intervention based on empowerment theory compared to an enhanced efficacious control condition among 515 high risk not-in-treatment MSM substance users. Effect sizes for sexual risk and substance use outcomes were moderate to large: HIV transmission risk frequency, d = 0.71 in the control versus 0.66 in the experimental group; number of anal sex partners, d = 1.04 versus 0.98; substance dependence symptoms, d = 0.49 versus 0.53; significant differences were not observed between conditions. Black MSM reduced their risks at a greater rate than White or Latino men. The findings point to a critically important research agenda to reduce HIV transmission among MSM substance users.

在美国，男男性行为者（MSM）中的吸毒人群属于感染艾滋病毒风险最高的群体之一。我们报告了一项随机试验的结果，该试验对基于赋权理论的小组性与吸毒风险降低干预措施的有效性进行了测试，并与515名未接受治疗的高风险男男性行为吸毒者的强化有效对照条件进行了比较。性风险和吸毒结果的效应量为中等到较大：艾滋病毒传播风险频率，对照组d = 0.71，实验组d = 0.66；肛交伴侣数量，d = 1.04对0.98；药物依赖症状，d = 0.49对0.53；各条件之间未观察到显著差异。黑人男男性行为者降低风险的速度比白人或拉丁裔男性更快。这些研究结果指出了一个至关重要的研究议程，即减少男男性行为吸毒者中的艾滋病毒传播。