Click-Evoked Gross Potentials and Single-Unit Thresholds in Acoustically Traumatized Cats

Click-evoked gross potentials were recorded from the round windows of 29 cats previously exposed to high-level sounds. The latency and amplitude of the gross neural components of these responses were determined and compared with the patterns of threshold shift measured in single auditory nerve fibers from the same 29 animals. Both of these electrophysiological measures were compared with the patterns of hair cell loss as seen in celloidin sections through the temporal bone. The correlations between single-unit abnormalities and cochlear pathology in these cases have been documented elsewhere. In this report, the correlations between gross-potential abnormalities and cochlear pathology are examined. The diagnostic potential of these correlations is discussed.

从29只先前暴露于高强度声音的猫的圆窗记录了点击诱发的总电位。测定了这些反应的总神经成分的潜伏期和振幅，并与在相同29只动物的单根听神经纤维中测量到的阈值偏移模式进行了比较。将这两种电生理测量结果与通过颞骨的火棉胶切片中所见的毛细胞丢失模式进行了比较。在这些病例中，单单位异常与耳蜗病理学之间的相关性已在其他文献中有所记载。在本报告中，研究了总电位异常与耳蜗病理学之间的相关性。讨论了这些相关性的诊断潜力。