Simplified indicator for assessing flow velocity by simulation

In order to simplify computation time for multi-exposure speckle imaging, we recently presented a new indicator of blood flow, i.e. the slope of the inverse square of the contrast values versus camera exposure time (kslope). In this paper we simulate a sequence of correlated dynamic speckle images to test the viability of kslope as an indicator of flow velocity. We find that the presence of static scattering doesn’t influence the linear relationship between the slope and flow velocity. We also show that the normalization can be performed to obtain equivalence relation between relative slope values and relative flow velocity. The computation can be greatly simplified for multi-exposure speckle imaging. This new indicator kslope can play an important role in quantitatively assessing tissue blood flow velocity.

为了简化多次曝光散斑成像的计算时间，我们最近提出了一种新的血流指标，即对比度值的平方反比与相机曝光时间的斜率（$k_{斜率}$）。在本文中，我们模拟了一系列相关的动态散斑图像，以测试$k_{斜率}$作为流速指标的可行性。我们发现静态散射的存在并不影响斜率与流速之间的线性关系。我们还表明，可以进行归一化以获得相对斜率值和相对流速之间的等效关系。对于多次曝光散斑成像，计算可以大大简化。这种新的指标$k_{斜率}$在定量评估组织血流速度方面可以发挥重要作用。