Base-Catalyzed Cascade 1,3-H Shift/Cyclization Reaction to Construct Polyaromatic Furans

A convenient new method was developed to prepare unfused polyaromatic furan derivatives from diynyl-1,6-diols through a novel base-catalyzed cascade 1,3-H shift/cyclization process. Deuterium experiments were performed to determine that the 1,3-H shift was the rate-determining step.

开发了一种便捷的新方法，通过一种新型的碱催化级联1,3 - H迁移/环化过程，从二炔基-1,6 -二醇制备非稠合多芳族呋喃衍生物。进行了氘代实验以确定1,3 - H迁移是决速步骤。