Leukocyte-Endothelial Interactions Following Myocardial Ischemia

Coronary heart disease (CHD) remains the single leading cause of mortality in American men and women. According to the American Heart Association, nearly 500,000 Americans die each year from CHD accounting for approximately 20% of all deaths nationwide. Over 1 million Americans will have a recurrent coronary attack or develop a new episode this year. In addition to the morbidity and mortality of CHD, billions of dollars are spent each year treating and preventing CHD. Accordingly, intensive investigative efforts are directed toward enhancing our understanding of heart disease and ultimately developing effective therapies to combat the deleterious consequences of CHD.

冠心病（CHD）仍然是美国男性和女性死亡的首要单一原因。据美国心脏协会称，每年有近50万美国人死于冠心病，约占全国所有死亡人数的20%。今年将有超过100万美国人再次发生冠心病发作或出现新的发病情况。除了冠心病的发病率和死亡率外，每年还花费数十亿美元用于治疗和预防冠心病。因此，大量的研究工作致力于增进我们对心脏病的了解，并最终开发出有效的治疗方法来对抗冠心病的有害后果。