Implementation of novel biomarkers in the diagnosis, prognosis, and management of acute kidney injury: executive summary from the tenth consensus conference of the Acute Dialysis Quality Initiative (ADQI).

Detection of acute kidney injury is undergoing a dynamic revolution of biomarker technology allowing greater, earlier, and more accurate determination of diagnosis, prognosis, and with powerful implication for management. Biomarkers can be broadly considered as any measurable biologic entity or process that allows differentiation between normal function and injury or disease. The ADQI (Acute Dialysis Quality Initiative) had its Ninth Consensus Conference dedicated to synthesis and formulation of the existing literature on biomarkers for the detection of acute kidney injury in a variety of settings. In the papers that accompany this summary, ADQI workgroups fully develop key concepts from a summary of the literature in the domains of early diagnosis, differential diagnosis, prognosis and management, and concurrent physiologic and imaging measures.

急性肾损伤的检测正在经历生物标志物技术的动态变革，从而能够更广泛、更早、更准确地确定诊断、预后，并对治疗管理具有重大意义。生物标志物大致可被视为任何可测量的生物实体或过程，它能够区分正常功能与损伤或疾病。急性透析质量倡议（ADQI）召开了第九次共识会议，专门综合和阐述了在各种情况下用于检测急性肾损伤的生物标志物的现有文献。在本总结附带的论文中，ADQI工作组从早期诊断、鉴别诊断、预后和管理以及同时进行的生理和影像学检测等领域的文献综述中充分阐述了关键概念。