A tutorial on asymmetric electrocatalysis.

Electrochemistry has emerged as a powerful means to enable redox transformations in modern chemical synthesis. This tutorial review delves into the unique advantages of electrochemistry in the context of asymmetric catalysis. While electrochemistry has historically been used as a green and mild alternative for established enantioselective transformations, in recent years asymmetric electrocatalysis has been increasingly employed in the discovery of novel asymmetric methodologies based on reaction mechanisms unique to electrochemistry. This tutorial review first provides a brief tutorial introduction to electrosynthesis, then explores case studies on homogenous small molecule asymmetric electrocatalysis. Each case study serves to highlight a key advance in the field, starting with the historic electrification of known asymmetric transformations and culminating with modern methods relying on unique electrochemical mechanistic sequences. Finally, we highlight case studies in the emerging reasearch areas at the interface of asymmetric electrocatalysis with biocatalysis and heterogeneous catalysis.

电化学已成为现代化学合成中实现氧化还原转化的一种强有力手段。这篇指导性综述深入探讨了电化学在不对称催化方面的独特优势。虽然电化学在历史上一直被用作已有的对映选择性转化的一种绿色温和替代方法，但近年来，不对称电催化在基于电化学独特反应机制的新型不对称方法的发现中越来越多地被应用。这篇指导性综述首先对电合成进行了简要的指导性介绍，然后探讨了均相小分子不对称电催化的案例研究。每个案例研究都旨在突出该领域的一个关键进展，从已知不对称转化的历史性电气化开始，到依赖独特电化学机制序列的现代方法达到高潮。最后，我们重点介绍了不对称电催化与生物催化和多相催化交叉的新兴研究领域的案例研究。