The GTPase Rab1 Is Required for NLRP3 Inflammasome Activation and Inflammatory Lung Injury

Uncontrolled inflammatory response during sepsis predominantly contributes to the development of multiorgan failure and lethality. However, the cellular and molecular mechanisms for excessive production and release of proinflammatory cytokines are not cle

脓毒症期间不受控制的炎症反应在多器官衰竭和致死性的发展中起主要作用。然而，促炎细胞因子过度产生和释放的细胞及分子机制尚不清楚。