Improving efficacy of biopesticides through understanding mode of action

通过了解作用方式提高生物农药的功效

• 批准号: IE230100103
• 负责人: Dr Amanda Padovan
• 金额: $ 33.22万
• 依托单位: Macquarie University
• 依托单位国家: 澳大利亚
• 项目类别: Early Career Industry Fellowships
• 财政年份: 2024
• 资助国家: 澳大利亚
• 起止时间: 2024-06-30 至 2028-03-30
• 项目状态: 未结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/IE230100103
• 关键词: Improving; efficacy; biopesticides; through; understanding; Improving; efficacy; biopesticides; through; understanding

Insecticides are used extensively to control agricultural pests, but options are increasingly limited owing to environmental and human health concerns. A biopesticide, Bt, provides a valuable ‘soft’ option for control of caterpillars that are amongst the world's most damaging insect pests. However, little is known about how ingested Bt kills insects and this knowledge gap constrains options to improve efficacy and to counter resistance. This project connects industry end users (Cotton RDC; Bayer CropScience) with research training (Macquarie University) and applied research (CSIRO) to model how Bt interacts with the insect gut. This model will make valuable contributions to ensuring sustained and improved efficacy of Bt biopesticides.

杀虫剂被广泛用于控制农业害虫，但由于环境和人类健康的关注，选择越来越限制。生物农药BT为控制世界上最具破坏性的害虫之一的毛毛虫提供了宝贵的“软”选择。但是，对于摄入的BT如何杀死昆虫，知识差距限制了提高效率和抵抗性的选择，知之甚少。该项目将行业最终用户（Cotton RDC； Bayer Cropscience）与研究培训（Macquarie University）和Applied Research（CSIRO）联系起来，以模拟BT与绝缘肠的相互作用。该模型将为确保BT生物农药的持续和提高效率做出宝贵的贡献。