Multifunctional Borylenes for Metal- and Boron-Mediated Reactions

用于金属和硼介导反应的多功能硼烯

• 批准号: RGPIN-2021-03056
• 负责人: Pranckevicius, Conor
• 金额: $ 2.11万
• 依托单位: University of British Columbia
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2022
• 资助国家: 加拿大
• 起止时间: 2022-01-01 至 2023-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=761672
• 关键词: Multifunctional; Borylenes; Metal; Boron; Mediated

As we progress into the 21st century, our society has become increasingly cognizant of our growing energy needs, our dwindling supply of traditional resources, and the global environmental challenges created by anthropogenic climate change. To address these issues, we must develop sustainable technology that emphasizes environmental stewardship. Inorganic chemistry is in a uniquely powerful position to make meaningful global impacts, as chemical industry is responsible for approximately 20% of all industrial energy consumption in North America, and around 90% of all chemical processes utilize catalysts to improve their energy efficiency. Recent successes, including the discovery of stable carbenes heralded the development of highly efficient carbene-supported inorganic catalysts for olefin metathesis and cross-coupling reactions, which served to drastically reduce the energy input required to access these important chemical intermediates. Additionally, the development of main group catalysis has provided the first alternatives to the use of rare transition metal catalysts in many reactions, providing the a new path towards sustainable resource use. Despite these successes, there is still much work to be done to transition our society toward dependence on sustainable resources and responsible management of our finite ones. To tackle these issues, my research program is divided into two streams that are unified under the concept of applying recent fundamental advances in main group chemistry to the catalytic and materials sciences, with a focus on the emerging applications of neutral boron(I) molecules known as borylenes. Our first stream will target borylene ligands for transition metals (TMs) that offer an unprecedented level of electron density to a TM center. This property makes them ideal candidates for the construction of new energy-saving catalysts for use in many industrially important reactions. A second stream will focus on the metal-free reactivity of borylenes, where the concepts learned in borylene and main group chemistry are united to produce new catalytic cycles involving challenging transformations such as C-H activation and the functionalization of molecular nitrogen that are based on earth abundant elements. Another application involves the involves the use of metal-free borylenes to generate new libraries of electronically flexible conjugated materials with applications as energy-saving electrode materials within rechargeable batteries. My research projects specifically target collaboration with Canadian industrial partners, and will strengthen Canada's role in in the development of environmentally friendly and sustainable technology to address some of the most pertinent challenges currently facing society. Students engaged in these multidisciplinary projects will be gain both the technical and communication skills that will allow them to take on leadership roles in green chemistry as they begin their independent careers.

随着我们进入21世纪，我们的社会越来越认识到我们日益增长的能源需求、我们日益减少的传统资源供应以及人为气候变化造成的全球环境挑战。为了解决这些问题，我们必须开发强调环境管理的可持续技术。无机化学在产生有意义的全球影响方面处于独特的有利地位，因为化学工业约占北美所有工业能源消耗的 20%，并且所有化学过程中约 90% 都利用催化剂来提高能源效率。最近的成功，包括稳定卡宾的发现，预示着用于烯烃复分解和交叉偶联反应的高效卡宾负载无机催化剂的开发，这大大减少了获取这些重要化学中间体所需的能量输入。此外，主族催化的发展为许多反应中使用稀有过渡金属催化剂提供了第一个替代方案，为可持续资源利用提供了新途径。尽管取得了这些成功，但要使我们的社会转向依赖可持续资源和对有限资源进行负责任的管理，仍有许多工作要做。 为了解决这些问题，我的研究计划分为两个部分，这两个部分统一在将主族化学的最新基本进展应用于催化和材料科学的概念下，重点是已知的中性硼（I）分子的新兴应用如硼甲苯。我们的第一个流将针对过渡金属 (TM) 的硼烯配体，为 TM 中心提供前所未有的电子密度水平。这一特性使它们成为构建用于许多工业重要反应的新型节能催化剂的理想候选者。第二个方向将重点关注硼烯的无金属反应性，其中将硼烯和主族化学中学到的概念结合起来，产生新的催化循环，涉及具有挑战性的转化，例如 C-H 活化和基于地球丰富的分子氮的官能化元素。另一个应用涉及使用无金属硼烯来生成新的电子柔性共轭材料库，并在可充电电池中用作节能电极材料。 我的研究项目专门针对与加拿大工业合作伙伴的合作，并将加强加拿大在开发环保和可持续技术方面的作用，以解决当前社会面临的一些最相关的挑战。参与这些多学科项目的学生将获得技术和沟通技能，使他们能够在开始独立职业生涯时在绿色化学领域发挥领导作用。