Contribution of synovial fibroblast cell subsets to the pathogenesis of knee osteoarthritis

滑膜成纤维细胞亚群对膝骨关节炎发病机制的贡献

• 批准号: 479219
• 负责人: Kapoor Mohit
• 金额: $ 38.73万
• 依托单位: University Health Network (Toronto)
• 依托单位国家: 加拿大
• 项目类别: Operating Grants
• 财政年份: 2023
• 资助国家: 加拿大
• 起止时间: 2023-03-01 至 2027-03-01
• 项目状态: 未结题
• 来源: https://webapps.cihr-irsc.gc.ca/decisions/p/project_details.html?applId=479219&lang=en
• 关键词: Fibrosis; Inflammation; Osteoarthritis; Sequencing; Synovium; Transcriptomics; Fibrosis; Inflammation; Osteoarthritis; Sequencing; Synovium; Transcriptomics

Osteoarthritis (OA) is a progressive, degenerative disease of the joints. Patients with OA experience pain, stiffness and loss of quality of life. There are no approved therapies to stop OA progression. The knee is made of a number of tissues including ca

骨关节炎（OA）是关节的进行性，退化性疾病。 OA患者经历疼痛，僵硬和生活质量丧失。没有批准的疗法可以阻止OA进展。膝盖由包括CA在内的许多组织制成