High resolution non-contact surface-roughness industrial laser scanning microscope

高分辨率非接触式表面粗糙度工业激光扫描显微镜

• 批准号: RTI-2018-00220
• 负责人: Yim, Evelyn
• 金额: $ 10.93万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642331
• 关键词: resolution; non; contact; surface; roughness

Advanced nano-fabrication technologies enable the research team to pursue inter-disciplinary researches in biomaterials and regenerative medicine, novel bio-adhesive, fuel cell and sensor development. Robust characterization of the nano-structure are vital for the research program. High resolution and efficient 3D imaging of large area samples will be needed in each of the research areas. Currently, at the University of Waterloo (UW), the team rely on conventional surface characterization methods such as scanning electronic microscopy (SEM) or atomic force microscopy (AFM), which require slow, manual measurement on small area, while sample preparation and contacting mode measurement will induce surface damages. These cause long delay in research and training, requiring additional research funding and manpower, and limiting the potential and return-on-investment of valuable engineering programs at UW. We propose the acquisition of a non-contact laser microscope with automated surface roughness analysis. The superiorities of the non-contact laser microscope include fast high-resolution image acquisition, motorized stage with auto-focusing and tile imaging for 3D characterization of large non-planar specimens. Non-contact measurement will eliminate surface damage and possibilities of artifacts. With a dual confocal system and multilayer mode, the non-contact laser microscope enables the analysis of multiple layers, which is essential to examine cell morphology on nano-structure. The system will be used to characterize a wide range of materials from prototypes of nano-structures on biomaterials, porous membrane for fuel cells, biosensors and biomedical devices that may be licensed and commercialized in the future. Thus, the non-contact laser microscope provide a versatile and high-throughput characterization that is needed by the research programs, and it can enable building of new research program and engaging broader research partners.

先进的纳米制造技术使研究团队能够在生物材料和再生医学、新型生物粘合剂、燃料电池和传感器开发等领域进行跨学科研究。纳米结构的稳健表征对于研究计划至关重要。每个研究领域都需要对大面积样品进行高分辨率和高效的 3D 成像。目前，滑铁卢大学 (UW) 的团队依赖于传统的表面表征方法，例如扫描电子显微镜 (SEM) 或原子力显微镜 (AFM)，这些方法需要在小面积上进行缓慢的手动测量，同时进行样品制备和接触模式测量会引起表面损伤。这些导致研究和培训的长期拖延，需要额外的研究资金和人力，并限制了华盛顿大学有价值的工程项目的潜力和投资回报。我们建议购买一台具有自动表面粗糙度分析功能的非接触式激光显微镜。非接触式激光显微镜的优势包括快速高分辨率图像采集、具有自动对焦功能的电动载物台以及用于大型非平面样本 3D 表征的平铺成像。非接触式测量将消除表面损伤和伪影的可能性。非接触式激光显微镜采用双共焦系统和多层模式，能够进行多层分析，这对于检查纳米结构上的细胞形态至关重要。该系统将用于表征各种材料，包括生物材料纳米结构原型、燃料电池多孔膜、生物传感器和未来可能获得许可和商业化的生物医学设备。因此，非接触式激光显微镜提供了研究项目所需的多功能和高通量表征，它可以帮助建立新的研究项目并吸引更广泛的研究合作伙伴。