High resolution non-contact surface-roughness industrial laser scanning microscope

高分辨率非接触式表面粗糙度工业激光扫描显微镜

• 批准号: RTI-2018-00220
• 负责人: Yim, Evelyn
• 金额: $ 10.93万
• 依托单位: University of Waterloo
• 依托单位国家: 加拿大
• 项目类别: Research Tools and Instruments
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=642331
• 关键词: resolution; non; contact; surface; roughness

Advanced nano-fabrication technologies enable the research team to pursue inter-disciplinary researches in biomaterials and regenerative medicine, novel bio-adhesive, fuel cell and sensor development. Robust characterization of the nano-structure are vital for the research program. High resolution and efficient 3D imaging of large area samples will be needed in each of the research areas. Currently, at the University of Waterloo (UW), the team rely on conventional surface characterization methods such as scanning electronic microscopy (SEM) or atomic force microscopy (AFM), which require slow, manual measurement on small area, while sample preparation and contacting mode measurement will induce surface damages. These cause long delay in research and training, requiring additional research funding and manpower, and limiting the potential and return-on-investment of valuable engineering programs at UW. We propose the acquisition of a non-contact laser microscope with automated surface roughness analysis. The superiorities of the non-contact laser microscope include fast high-resolution image acquisition, motorized stage with auto-focusing and tile imaging for 3D characterization of large non-planar specimens. Non-contact measurement will eliminate surface damage and possibilities of artifacts. With a dual confocal system and multilayer mode, the non-contact laser microscope enables the analysis of multiple layers, which is essential to examine cell morphology on nano-structure. The system will be used to characterize a wide range of materials from prototypes of nano-structures on biomaterials, porous membrane for fuel cells, biosensors and biomedical devices that may be licensed and commercialized in the future. Thus, the non-contact laser microscope provide a versatile and high-throughput characterization that is needed by the research programs, and it can enable building of new research program and engaging broader research partners.

先进的纳米制作技术使研究团队能够从事生物材料和再生医学，新型生物粘合剂，燃料电池和传感器开发方面的学科研究。纳米结构的强大表征对于研究计划至关重要。在每个研究领域，都需要对大面积样品进行高分辨率和有效的3D成像。目前，在滑铁卢大学（UW），团队依赖于常规的表面表征方法，例如扫描电子显微镜（SEM）或原子力显微镜（AFM），这些方法需要在小面积上进行缓慢，手动测量，而样品制备和接触模式测量将造成表面损害。这些会导致研究和培训的长时间延迟，需要额外的研究资金和人力，并限制了UW上有价值的工程计划的潜力和回报。我们提出了具有自动表面粗糙度分析的非接触激光显微镜的获取。非接触式激光显微镜的优势包括快速的高分辨率图像采集，具有自动焦点和瓷砖成像的机动阶段，用于3D表征大型非平面标本。非接触式测量将消除伪影的表面损伤和可能性。使用双共聚焦系统和多层模式，非接触式激光显微镜可以分析多层，这对于检查纳米结构的细胞形态至关重要。该系统将用于表征从生物材料的纳米结构的原型，燃料电池的多孔膜，生物传感器和生物医学设备的多孔膜，这些材料将来可能会在未来获得许可和商业化。因此，非接触式激光显微镜提供了研究计划所需的多功能和高通量表征，并且可以使建立新的研究计划并吸引更广泛的研究合作伙伴。