Analytical and Computational Tools for Long-Pulse Photoacoustics

长脉冲光声学的分析和计算工具

• 批准号: RGPIN-2016-04190
• 负责人: Baddour, Natalie
• 金额: $ 2.4万
• 依托单位: University of Ottawa
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=638757
• 关键词: Analytical; Computational; Tools; Long; Pulse

Photoacoustic signal generation is a technique which has demonstrated great potential for non-invasive medical tomography. With this technique, a short-pulse of laser energy is used on a sample. The absorbed energy produces a small temperature rise, which in turn induces a change in pressure inside the sample due to thermal expansion. This pressure acts as a source of ultrasound waves which can be detected by ultrasound detectors positioned outside the sample. Since there is a large difference between how blood and surrounding tissue absorb the light energy, this provides a way to look for anomalies in the tissue. This approach is thus suitable for imaging of the micro-vascular system, tumour detection or tissue characterization.

光声信号生成是一种在非侵入性医学断层扫描方面显示出巨大潜力的技术。通过这种技术，可以在样品上使用短脉冲激光能量。吸收的能量会产生小幅温升，进而由于热膨胀而引起样品内部压力的变化。该压力充当超声波源，可以通过位于样品外部的超声波检测器检测到。由于血液和周围组织吸收光能的方式存在很大差异，这提供了一种寻找组织异常的方法。因此，该方法适用于微血管系统成像、肿瘤检测或组织表征。