Development of New Methods for Quantitative MRI

定量 MRI 新方法的开发

• 批准号: RGPIN-2017-04006
• 负责人: Wilman, Alan
• 金额: $ 3.35万
• 依托单位: University of Alberta
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=632942
• 关键词: Development; New; Methods; Quantitative; MRI

Magnetic Resonance Imaging (MRI) is very useful for examining soft tissue in the body and is still rapidly evolving in capability and increasing in use. One of the limitations of MRI is it tends to not provide exact tissue measurements, instead making relative measurements by comparing the signal in different areas. If fast and exact quantitative tissue measures could be developed for MRI, it could further its ability to offer precise information which would be valuable for medical imaging and industrial uses. Our laboratory specializes in the generation of new MRI methods by exploiting the MRI physics underlying each form of image contrast. Our long term goal is the continual development of novel methods that increase the value of MRI and are based on understanding MRI physics and its relationship to human tissue properties. This research proposal will develop new means of performing quantitative MRI, focusing on three unique quantitative techniques. The three areas of interest are emerging areas of MRI application that require further evolution to become practical tools.

磁共振成像 (MRI) 对于检查体内软组织非常有用，并且其功能仍在快速发展且使用不断增加。 MRI 的局限性之一是它往往无法提供精确的组织测量，而是通过比较不同区域的信号进行相对测量。如果可以为 MRI 开发快速、准确的定量组织测量方法，则可以进一步提高其提供精确信息的能力，这对于医学成像和工业用途非常有价值。我们的实验室专门通过利用每种形式的图像对比度背后的 MRI 物理原理来生成新的 MRI 方法。我们的长期目标是在了解 MRI 物理原理及其与人体组织特性的关系的基础上，不断开发新方法来提高 MRI 的价值。该研究计划将开发执行定量 MRI 的新方法，重点关注三种独特的定量技术。这三个感兴趣的领域是 MRI 应用的新兴领域，需要进一步发展才能成为实用工具。