Appetite regulation in humans: effect of sex hormones and exercise intensity

人类食欲调节：性激素和运动强度的影响

• 批准号: RGPIN-2016-06118
• 负责人: Hazell, Tom
• 金额: $ 1.82万
• 依托单位: Wilfrid Laurier University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631524
• 关键词: Appetite; regulation; humans; effect; sex

The idea that exercise may produce fat loss without dietary intervention is controversial, as aerobic exercise alone frequently results in fat loss in males but is less effective in females. Recently, we demonstrated an intense model of high-intensity interval training (HIIT) known as sprint interval training (SIT; 4-6 repeated “all-out” 30 s efforts separated by 4 min active rest) induced fat loss in both males and females. However, the magnitude of the fat loss was greater in males. To explore the mechanism for the ability of interval training to induce fat loss, we measured post-exercise metabolism over 24 h across three experimental sessions (no exercise, SIT, moderate-intensity aerobic exercise). Despite the drastically reduced exercise volume (2 min of exercise SIT vs 30 min aerobic), SIT induced a small but prolonged increase in post-exercise metabolism, which likely contributes to the SIT-induced fat loss. However, this increase in post-exercise metabolism is similar across sex. This suggests sex hormones and exercise intensity affect appetite-regulation.

运动可以在不进行饮食干预的情况下减少脂肪的想法是有争议的，因为单独有氧运动经常导致男性脂肪减少，但对女性效果较差。最近，我们展示了一种称为高强度间歇训练（HIIT）的强化模型。冲刺间歇训练（SIT；4-6 次重复“全力以赴”的 30 秒训练，中间间隔 4 分钟的主动休息）可导致男性和女性的脂肪减少，但男性的脂肪减少幅度更大。能力机制尽管运动量大幅减少（2 分钟的静坐运动与 30 分钟的有氧运动），但我们还是通过三个实验（无运动、静坐、中等强度有氧运动）测量了 24 小时内的运动后代谢情况。 SIT 会引起运动后新陈代谢的小幅但长期的增加，这可能有助于 SIT 引起的脂肪减少。然而，这种运动后新陈代谢的增加在不同性别之间是相似的。运动强度影响食欲调节。