Appetite regulation in humans: effect of sex hormones and exercise intensity

人类食欲调节：性激素和运动强度的影响

• 批准号: RGPIN-2016-06118
• 负责人: Hazell, Tom
• 金额: $ 1.82万
• 依托单位: Wilfrid Laurier University
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2017
• 资助国家: 加拿大
• 起止时间: 2017-01-01 至 2018-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=631524
• 关键词: Appetite; regulation; humans; effect; sex

The idea that exercise may produce fat loss without dietary intervention is controversial, as aerobic exercise alone frequently results in fat loss in males but is less effective in females. Recently, we demonstrated an intense model of high-intensity interval training (HIIT) known as sprint interval training (SIT; 4-6 repeated “all-out” 30 s efforts separated by 4 min active rest) induced fat loss in both males and females. However, the magnitude of the fat loss was greater in males. To explore the mechanism for the ability of interval training to induce fat loss, we measured post-exercise metabolism over 24 h across three experimental sessions (no exercise, SIT, moderate-intensity aerobic exercise). Despite the drastically reduced exercise volume (2 min of exercise SIT vs 30 min aerobic), SIT induced a small but prolonged increase in post-exercise metabolism, which likely contributes to the SIT-induced fat loss. However, this increase in post-exercise metabolism is similar across sex. This suggests sex hormones and exercise intensity affect appetite-regulation.

运动可能会导致脂肪减少而无需饮食干预的想法是有争议的，因为仅有氧运动经常导致雄性脂肪减少，但在女性中的效果较小。最近，我们展示了一种强烈的高强度间隔训练（HIIT）的强烈模型，称为Sprint间隔训练（SIT； 4-6重复的“全外” 30 S努力，分别为4分钟的活跃休息）诱导了男性和女性的脂肪损失。然而，探索间隔训练能力诱发脂肪减少的能力的机制的脂肪流失的大小，我们在三个实验性会议上测量了24小时的运动后代谢（无运动，SIT，SIT，中等强度有氧运动）。尽管运动体积急剧减少（运动现场2分钟与30分钟有氧运动），但坐骨运动后诱发了小而长时间的运动后代谢，这可能导致情绪诱发的脂肪损失。但是，运动后代谢的增加在性别中相似。这表明性恐怖和运动强度会影响食欲调节。