Multibody dynamic modeling of the upper limb for the quantification of muscle force co-contraction and synergy strategies during motion

上肢多体动力学建模，用于量化运动过程中的肌肉力量协同收缩和协同策略

• 批准号: 402002-2013
• 负责人: Raison, Maxime
• 金额: $ 1.75万
• 依托单位: École Polytechnique de Montréal
• 依托单位国家: 加拿大
• 项目类别: Discovery Grants Program - Individual
• 财政年份: 2015
• 资助国家: 加拿大
• 起止时间: 2015-01-01 至 2016-12-31
• 项目状态: 已结题
• 来源: https://www.nserc-crsng.gc.ca/ase-oro/Details-Detailles_eng.asp?id=573124
• 关键词: Multibody; dynamic; modeling; upper; limb

The goal of this biomedical engineering research program is to quantify individual muscle forces during upper limb motion in healthy adults. This will also enable to explain the temporal evolution of muscle strategies of co-contraction, i.e. opposite actions of muscles on each side of a joint, and synergy, i.e. joint actions of muscles on the same side of a joint, for fundamental knowledge and future innovative applications in sports, robotics, rehabilitation, orthopedics, ergonomics and/or prevention. The program includes 3 specific objectives: 1. Develop a biofidelic and personalized dynamic model of the upper limb, enabling to quantify muscle forces during motion. 2. Validate it as far as possible using nerve motor blocs, i.e. locally anesthetizing selected muscles. 3. Use it to understand the muscle overactuation strategies during flexion/extension, pronation/supination, and pointing task. The novelty of this research program is double: 1. The goal will be achieved through a unique scientific approach based on the development of a biofidelic and personalized dynamic method assessing the muscle forces in the human body in motion. 2. This objective of improving the understanding of muscle overactuation in the human body during motion is completely innovant in literature and of great interest concerning current demands for personalized muscle force quantification in the clinical and industrial domains. The main fields of applications will be rehabilitation and orthopedic domain for the evaluation and follow-up of musculo-skeletal pathologies and the design of assistive device, and the sport domain for the analysis and improvement of athletic performance. The trainingship of undergraduate and graduate students is a fundamental part of this multi-disciplinary research program, which will allow them to develop strong skills in applied mechanics (biomechanical modeling, multibody dynamics) and experimentation (design of experimental protocol, analyses of error, reproducibility and sensitivity). Finally, this research program will also enable to develop international collaborations.

该生物医学工程研究计划的目的是在健康成年人的上肢运动中量化单个肌肉力量。这也将能够解释共同取决的肌肉策略的时间演变，即肌肉在关节的两侧的相反作用，以及协同作用，即肌肉在关节的同一方面的共同行动，用于基本知识和未来在体育，机器人，居住，校园，矫形器，校园和预测中的基本知识和未来的创新应用。该程序包括3个特定目标：1。开发上肢的生物层和个性化动态模型，从而在运动过程中量化肌肉力量。 2。使用神经运动集团（即局部麻醉选定的肌肉）尽可能验证它。 3。使用它来了解屈曲/扩展，旋转/旋转和指向任务期间的肌肉超过策略。 该研究计划的新颖性是双重的： 1。将通过基于生物体质和个性化动态方法的开发来评估人体中运动中的肌肉力量的独特科学方法来实现目标。 2。在运动过程中，这一目标是在文献中完全创新的，这是对临床和工业领域中对个性化肌肉力量量化的当前需求的极大兴趣。应用的主要领域将是康复和骨科领域，用于评估和随访肌肉骨骼病理和辅助设备的设计，以及用于分析和改善运动表现的运动领域。本科生和研究生的培训是该多学科研究计划的基本组成部分，这将使他们能够发展出强大的应用力学技能（生物力学建模，多体动力学）和实验（实验协议，误差，可重复性和灵敏度的分析）。最后，该研究计划还将能够开发国际合作。