Communication Outcomes for Naming Treatments in Aphasia

失语症命名治疗的沟通结果

• 批准号: 7850035
• 负责人: Anastasia Marie Raymer
• 金额: $ 3.46万
• 依托单位: OLD DOMINION UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2009
• 资助国家: 美国
• 起止时间: 2009-07-17 至 2011-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7850035
• 关键词: Academic Research Enhancement Awards; Acquired Aphasia; Activities of Daily Living; Address; Affect; Aftercare; Anomia; Aphasia; Behavior Therapy; Clinical Trials; Communication; Development Plans; Effectiveness; Experimental Designs; Failure; Gestures; Goals; Health; Impairment; Individual; Inferior; Language; Language Disorders; Lead; Left; Left cerebral hemisphere; Life; Link; Measures; Methods; Modeling; Names; Nickel; Outcome; Participant; Patients; Pattern; Process; Production; Randomized Clinical Trials; Research; Research Design; Retrieval; Sampling; Semantics; Speech Therapy; Staging; Stroke; Symptoms; Testing; Thinking; Training; Treatment Protocols; Treatment outcome; base; disability; effective therapy; follow-up; frontal lobe; lexical; neuroimaging; prospective; public health relevance; response; treatment effect

DESCRIPTION (provided by applicant): Thousands of individuals each year suffer a stroke affecting the left hemisphere of the brain and develop aphasia, an acquired language disability. One of the most common symptoms of aphasia is word retrieval impairment, which can disrupt the ability to express even basic thoughts and needs. Several behavioral treatment methods have been described that have positive impact on word retrieval abilities, largely in constrained picture naming tasks. The true impact of treatment gains need to be appreciated as well during conversational word retrieval, that is, at the level of communication activities/participation (WHO, 2001). Much less evidence is available about the most effective treatments leading to positive outcomes in discourse level- communication. Further, word retrieval treatment studies have often shown largest treatment effects in individuals with mild-to-moderate impairments, often characterized by failure in lexical phonologic stages of word retrieval, and more limited effects in individuals with severe semantically-based word retrieval impairments. That is, those with the greatest needs to communicate, if only with single words, have the poorest response to word retrieval treatment. The purpose of this project is to investigate modified versions of two word retrieval treatment approaches, errorless naming treatment and verbal+gestural treatment, for their effects not only for picture naming, but also for measures of communication activities/participation. Further, we will examine treatment outcomes in individuals with phonologic and semantic word retrieval impairments. Because our treatments are still in exploratory stages of development, we plan to test 16 participants, 8 in each treatment protocol, using single participant multiple baseline experimental designs replicated across word sets and participants. Half of the participants receiving each treatment will have semantically-based impairments. We will examine the effects of our treatments for word retrieval and gesture production in picture naming and discourse samples, as well as in communication rating scales measured at treatment completion and at one month follow up. Finally, we will compare outcomes for picture naming probes administered daily versus those administered at pre- and post- treatment to determine any impact of this errorful research design for errorless training. PUBLIC HEALTH RELEVANCE: Hundreds of thousands of individuals are living with the consequences of stroke, including aphasia, an impairment in the ability to understand and express oneself through words and sentences. This project aims to identify more effective methods of speech therapy to assist individuals who are recovering from stroke and aphasia to maximize their ability to express ideas and basic needs during daily life activities.

描述（由申请人提供）：每年有数千人遭受影响大脑左半球的中风并出现失语症（一种后天性语言障碍）。失语症最常见的症状之一是单词检索障碍，这可能会破坏表达基本思想和需求的能力。已经描述了几种对单词检索能力有积极影响的行为治疗方法，主要是在受限的图片命名任务中。在会话单词检索过程中，即在交流活动/参与的层面上，也需要认识到治疗效果的真正影响（WHO，2001）。关于最有效的治疗方法可在话语层面的沟通中带来积极结果的证据要少得多。此外，单词检索治疗研究通常表明，对具有轻度至中度障碍的个体具有最大的治疗效果，其特征通常是单词检索的词汇语音阶段的失败，而对具有严重基于语义的单词检索障碍的个体的效果则更为有限。也就是说，那些最需要交流的人，即使只使用单个单词，对单词检索治疗的反应也最差。该项目的目的是研究两个词检索处理方法的修改版本，即无错误命名处理和言语+手势处理，其不仅对图片命名有影响，而且对交流活动/参与的衡量也有影响。此外，我们将检查具有语音和语义单词检索障碍的个体的治疗结果。由于我们的治疗仍处于探索性开发阶段，因此我们计划使用在单词集和参与者之间复制的单参与者多基线实验设计来测试 16 名参与者，每个治疗方案 8 名参与者。接受每种治疗的参与者中有一半会出现基于语义的障碍。我们将检查我们的单词检索和手势产生治疗对图片命名和话语样本的影响，以及在治疗完成和一个月随访时测量的沟通评级量表的效果。最后，我们将比较每天进行的图片命名探针的结果与治疗前和治疗后进行的结果，以确定这种错误的研究设计对无错误训练的任何影响。公共卫生相关性：数十万人患有中风的后果，包括失语症，即通过单词和句子理解和表达自己的能力受损。该项目旨在寻找更有效的言语治疗方法，以帮助中风和失语症康复者最大限度地提高他们在日常生活活动中表达想法和基本需求的能力。

项目成果

Intensity of aphasia therapy: evidence and efficacy.

失语症治疗的强度：证据和功效。

• 发表时间: 2011-12
• 作者: Cherney, Leora R;Patterson, Janet P;Raymer, Anastasia M
• 通讯作者: Raymer, Anastasia M

Contrasting effects of errorless naming treatment and gestural facilitation for word retrieval in aphasia.

无错误命名治疗和手势促进对失语症单词检索的效果对比。

• 发表时间: 2012
• 影响因子: 2.7
• 作者: Raymer, Anastasia M;McHose, Beth;Smith, Kimberly G;Iman, Lisa;Ambrose, Alexis;Casselton, Colleen
• 通讯作者: Casselton, Colleen