Diverse Predoctoral Training in Genetics

遗传学方面的多样化博士前培训

• 批准号: 10620735
• 负责人: DAVID W. THREADGILL
• 金额: $ 17.21万
• 依托单位: TEXAS A&M UNIVERSITY HEALTH SCIENCE CTR
• 依托单位国家: 美国
• 财政年份: 2020
• 资助国家: 美国
• 起止时间: 2020-07-01 至 2025-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10620735
• 关键词: Genetic; Training; pre-doctoral

PROJECT SUMMARY Texas A&M University has a long history of training in the genetic sciences, with the first graduate degree having been awarded in 1919. The first Interdisciplinary Program (IDP) in Genetics was the first IDP established at Texas A&M in 1983, and has been at the forefront of diversifying not only the trainee pool that will contribute to a diversified workforce, but is also leading in the preparedness of students for diverse career paths. The Genetics IDP preceptors have world-renowned research programs providing unique opportunities for trainees to perform dissertation research in laboratories using cutting-edge technologies that are addressing important and impactful questions in modern genetics that impact human health and well-being, while also having extensive mentoring and career development opportunities. This innovative training program aims to be a model for ‘preparing diverse scientists for a diverse workforce’. The Genetics IDP has developed several initiatives and partnerships that have resulted in a dramatic increase in diversity of applicants and matriculates to the program. Similar to the need for a diverse genetics workforce, efforts are needed to diversify preparedness for future workforce needs and career opportunities. Modern training in genetics and the sub-discipline of genomics not only requires mastering classical Mendelian and quantitative genetics, but expertise in big data, interpersonal interactions that is essential for convergence research, and project management that can be applied to diverse career opportunities. The training program, which will support 4 new trainees each year for 2-year appointments (8 concurrent trainees), is designed to train the next generation of scholar in modern genetics by providing contemporary skills and exposure to the increasingly broad range of career opportunities that these scholars will pursue in order to have a profound impact on the future of genetic sciences. The goals of the training program are to: 1) Provide doctoral students with balanced research and training opportunities that span the continuum from basic science to applied applications and the scientific knowledge needed to excel in modern genetic sciences irrespective of career path; 2) Offer a rigorous didactic training that provides the fundamentals in Mendelian and quantitative genetics, statistics and experimental design, rigor and reproducibility, biostatistics, big data computation skills, and a core set of competencies in communication, interpersonal interactions, and leadership and team science that will be required for successful careers in academia, industry and government; and 3) Ensure that trainees develop appreciation for, familiarity with, and exposure to various career opportunities for well-trained geneticists through mentorship and introduction to experts in various fields.

项目概要 德克萨斯农工大学在遗传科学方面拥有悠久的培训历史，其第一个研究生学位是 于 1919 年授予。第一个遗传学跨学科项目 (IDP) 是在 德克萨斯 A&M 公司成立于 1983 年，一直处于多元化的最前沿，这不仅有助于培养学员队伍 多元化的劳动力队伍，同时也在学生为多样化职业道路做好准备方面处于领先地位。 IDP 导师拥有世界知名的研究项目，为学员提供独特的表演机会 使用尖端技术在实验室进行论文研究，解决重要且有影响力的问题 现代遗传学中影响人类健康和福祉的问题，同时也有广泛的指导 这个创新的培训计划旨在成为“准备多样化”的典范。 遗传学 IDP 制定了多项举措和合作伙伴关系， 与该计划类似，申请人和录取者的多样性急剧增加。 需要多样化的遗传学劳动力，需要努力使未来劳动力需求的准备多样化 和职业机会不仅需要遗传学和基因组学子学科的现代培训。 掌握经典孟德尔和定量遗传学，但在大数据、人际互动方面的专业知识 对于融合研究和可应用于多种职业的项目管理至关重要 培训计划，每年将支持 4 名新学员进行为期 2 年的培训（8 并发学员），旨在通过提供现代遗传学知识来培训下一代学者 这些学者将掌握当代技能并接触到日益广泛的职业机会 追求对遗传科学的未来产生深远影响的培训计划的目标。 目的是： 1）为博士生提供跨越连续体的均衡研究和培训机会 从基础科学到应用应用以及现代遗传学所需的科学知识 2）提供严格的教学培训，提供基础知识 孟德尔和定量遗传学、统计学和实验设计、严谨性和再现性、生物统计学、 大数据计算技能，以及沟通、人际互动等方面的一套核心能力 在学术界、工业界和政府部门取得成功职业生涯所需的领导力和团队科学； 3) 确保学员欣赏、熟悉并接触各种职业 通过指导和介绍各个领域的专家，为训练有素的遗传学家提供机会。

项目成果

Ultracontinuous Single Haplotype Genome Assemblies for the Domestic Cat (Felis catus) and Asian Leopard Cat (Prionailurus bengalensis).

家猫（Felis catus）和亚洲豹猫（Prionailurus bengalensis）的超连续单倍型基因组组装。

• 发表时间: 2021
• 作者: Bredemeyer, Kevin R;Harris, Andrew J;Li, Gang;Zhao, Le;Foley, Nicole M;Roelke;O'Brien, Stephen J;Lyons, Leslie A;Warren, Wesley C;Murphy, William J
• 通讯作者: Murphy, William J

A lytic transglycosylase connects bacterial focal adhesion complexes to the peptidoglycan cell wall.

裂解性转糖基酶将细菌粘着斑复合物连接到肽聚糖细胞壁。

• 发表时间: 2024-04-04
• 作者: Carbo, Carlos Ramirez;Faromiki, Olalekan G;Nan, Beiyan
• 通讯作者: Nan, Beiyan

Single-haplotype comparative genomics provides insights into lineage-specific structural variation during cat evolution.

单倍型比较基因组学提供了对猫进化过程中谱系特异性结构变异的见解。

• 发表时间: 2023-11
• 影响因子: 30.8
• 作者: Bredemeyer, Kevin R;Hillier, LaDeana;Harris, Andrew J;Hughes, Graham M;Foley, Nicole M;Lawless, Colleen;Carroll, Rachel A;Storer, Jessica M;Batzer, Mark A;Rice, Edward S;Davis, Brian W;Raudsepp, Terje;O'Brien, Stephen J;Lyons, Leslie A;Warre
• 通讯作者: Warre

Tree House Explorer: A Novel Genome Browser for Phylogenomics.

Tree House Explorer：用于系统基因组学的新型基因组浏览器。

• 发表时间: 2022-06-14
• 影响因子: 10.7
• 作者: Harris, Andrew J;Foley, Nicole M;Williams, Tiffani L;Murphy, William J
• 通讯作者: Murphy, William J