Data & Information Tech Core - Athey

数据

基本信息

批准号：
9132217
负责人：
CHARLES F BURANT
金额：
$ 15万
依托单位：
UNIVERSITY OF MICHIGAN AT ANN ARBOR
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至 2019-08-31
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9132217
关键词：
Archives Bioinformatics Biological Chemicals Chromatography Clinical Communities Complex Data Data Analyses Data Repository and Coordinating Center Data Set Databases Deposition Development Ensure Environment Goals Health Insurance Portability and Accountability Act Health system Individual Information Technology Instruction Knowledge Laboratories Lead Libraries Link Logistics Management Information Systems Maps Metabolic Metadata Methodology Methods Michigan Mind Mining Monitor National Center for Integrative Biomedical Informatics Output Phase Plasma Policies Procedures Process Research Research Infrastructure Research Personnel Resource Sharing Sampling Scientist Secure Specimen Statistical Data Interpretation System Time Training United States National Institutes of Health Universities Work computerized data processing cost data acquisition data archive data management data sharing data visualization health data high throughput analysis industry partner instrument investigator training metabolic profile metabolome metabolomics metabolomics resource operation outreach programs research study statistics support network tool web based interface

项目摘要

PROJECT SUMMARY (See Instructions): The Data and Information Technology Core of the Michigan Regional Comprehensive Metabolomics Resource Core (MRC2) will provide expertise for the analysis of spectral data from directed metabolomics data and provide important tools and research in the analysis of high-throughput, untargeted metabolite analysis used wider profiling of the metabolome. The identification of compounds in the untargeted metabolomics profile will be enhanced by the availability of a library of nearly 748 authentic metabolites whose spectral features have been determined on reverse phase and hydrophilic interaction chromatography (HILIC) time of flight (TOF) as well as a library of known unknowns' identified in nearly 500 plasma samples. The Core will also provide procedures for data normalization prior to data analysis. The Core also will be responsible for data curation, annotation and storage and will work with the Data Repository and Coordinating Center (DRCC) to provide raw and normalized of experiments performed in the core. The Data and Information Technology Core will work with IT teams within the University of Michigan to maintain, troubleshoot and upgrade the Information Technology infrastructure of the MRC2.

项目摘要（请参阅说明）：密歇根州区域全面代谢组学资源核心（MRC2）的数据和信息技术核心将为有指示的代谢组学数据分析光谱数据提供专业知识，并在高直发，无目标的代谢物分析的高位分析中提供了重要的工具和研究。通过近748个真实的代谢产物的库可获得未靶向的代谢组学概况中化合物的鉴定，其光谱特征已在反相和水上相互作用色谱（HILIC）飞行时间（TOF）（TOF）以及近500个plassples中标识的未知库中确定。核心还将在数据分析之前提供数据归一化的过程。核心还将负责数据策展，注释和存储，并将与数据存储库和协调中心（DRCC）一起使用，以提供对核心中执行的实验的原始和归一化的。数据和信息技术核心将与密歇根大学内的IT团队合作，以维护，故障排除和升级MRC2的信息技术基础架构。