Vascular Biology Training Grant

血管生物学培训补助金

• 批准号: 9057088
• 负责人: M. LUISA IRUELA-ARISPE
• 金额: $ 43.53万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2002
• 资助国家: 美国
• 起止时间: 2002-04-01 至 2018-03-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9057088
• 关键词: Biology; Blood Vessels; Grant; Training

DESCRIPTION (provided by applicant): Research in vascular biology has been responsible for remarkable changes in how we prevent, monitor and treat cardiovascular disease. The last fifty years have witnessed a transformation in patient care, increase in life expectancy and improvement in the quality of lives of those afflicted with vascular problems. It is through training of the next generation that we have made these achievements and it is through training that we will continue to make additional improvements in prevention and health care. The present application request funds to continue the interdisciplinary training of graduate students and post-doctoral fellows in vascular biology. In particular we aim at developing scientists who can: (1) "speak" various languages (metabolomics, pathology, molecular biology, genomics, and biomathematics), (2) integrate information and think towards (3) solving real clinical problems. To achieve these goals we have developed a multi-mentorship approach, novel didactic components and incorporated an interactive exposure to medicine into the structure of the training. UCLA houses a tremendous resource of interdisciplinary groups whose research focuses in vascular biology. The group includes 27 laboratories that currently offer training to 124 graduate students and post-doctoral fellows. It is this community that constitutes the pillars of a unique training program for the next generation of investigators in vascular biology. Being the only Vascular Biology Training grant in Los Angeles and one in four in California, we have trained 28 graduate students and post-doctoral fellows since 2002. These have produced 101 peer-reviewed publications while in the program and 9 have progressed to develop independent research groups in industry and universities across the nation. Furthermore, the activities associated with the training program have catalyzed interactions between groups intensifying collaborative activities. On the average 10 peer reviewed publications show the participation of two or more laboratories each year. Here, we request funding for 7 pre and 3 post-doctoral fellows / year, in which 2-3 new graduate students and either 1 or 2 post-doctoral fellows will enter the program each year. It is also our goal to actively seek and promote training and engagement of underrepresented minority groups (since 2002 we have a 21% minority trainee representation). It is an important objective of this program to be at the forefront of innovation in vascular biology education with strong emphasis in research integrity and ethics. In this current renewal we proposed the implementation of several new strategies to attain these goals and further improve the participation of minorities and the quality of training in vascular research. The success of this training program has engendered enthusiasm by the School of Medicine, College of Letters and Sciences and the Graduate Division at UCLA all of which have committed to provide additional institutional support towards activities developed by the VBTP.

描述（由申请人提供）：血管生物学研究已导致我们预防，监测和治疗心血管疾病的显着变化。过去的五十年见证了患者护理的转变，预期寿命的提高以及患有血管问题的人的生活质量的改善。正是通过培训下一代我们取得了这些成就，正是通过培训，我们将继续对预防和医疗保健进行进一步的改进。本申请要求资金继续对研究生和血管生物学的博士后研究员进行跨学科培训。特别是我们旨在发展可以：（1）“说”各种语言（代谢组学，病理学，分子生物学，基因组学和生物护理学），（2）对（2）将信息整合在一起并考虑（3）解决实际临床问题的思维。为了实现这些目标，我们开发了一种多头方法，新颖的教学成分，并将对医学的互动式接触纳入培训结构。加州大学洛杉矶分校（UCLA）拥有跨学科群体的巨大资源，其研究重点是血管生物学。该小组包括27个实验室，目前为124名研究生和博士后研究员提供培训。正是这个社区构成了下一代血管生物学研究人员的独特培训计划的支柱。自2002年以来，我们是洛杉矶唯一的血管生物学培训补助金，在加利福尼亚州的四分之一中，我们已经培训了28名研究生和博士后研究员。在该计划和9个计划中，这些培训已经产生了101个同行评审的出版物，而9个已经发展为在全国各地行业和大学中开发独立的研究小组。此外，与培训计划相关的活动催化了加强协作活动的群体之间的互动。平均10个同行评审出版物显示，每年两个或更多实验室的参与。在这里，我们要求为7个前和3名博士后研究员 /年提供资金，其中2-3名新研究生以及1或2个博士后研究员每年将进入该计划。我们的目标也是积极寻求和促进代表性不足的少数群体的培训和参与（自2002年以来，我们拥有21％的少数族裔学员代表）。该计划成为血管生物学教育创新的最前沿，这是一个重要的目标，并强烈重视研究完整性和道德。在此目前的续约中，我们提出了实施几种新策略来实现这些目标并进一步改善少数民族参与以及培训质量的血管研究。该培训计划的成功引起了医学院，文学学院和加州大学洛杉矶分校的研究生部门的热情，所有这些都致力于为VBTP开发的活动提供更多的机构支持。