Center for Biomedical and Health Research Excellence (CBHRE)

生物医学和健康卓越研究中心 (CBHRE)

• 批准号: 9108169
• 负责人: Adebayo O. Oyekan
• 金额: $ 175.2万
• 依托单位: TEXAS SOUTHERN UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 1986
• 资助国家: 美国
• 起止时间: 1986-09-30 至 2019-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9108169
• 关键词: Accounting; Affect; Award; Biochemical; Biological; Biomedical Research; Cardiovascular Diseases; Cardiovascular system; Cause of Death; Cessation of life; Collaborations; Communities; Development; Diabetes Mellitus; Disease; Environment; Evaluation; Extramural Activities; Fostering; Future; Genomics; Goals; Grant; Health; Institutes; Laboratory Research; Lead; Mainstreaming; Malignant Neoplasms; Marshal; Minority; Molecular Biology; Monitor; Morbidity - disease rate; Outcome; Pharmacology; Pilot Projects; Population; Process; Proteomics; Publications; Recommendation; Research; Research Infrastructure; Research Personnel; Research Support; Resources; Science; Services; Stroke; Texas; United States National Institutes of Health; Universities; University resources; base; clinically relevant; college; design; economic cost; environmental toxicology; health disparity; mortality; programs; prospective

DESCRIPTION (provided by applicant): Texas Southern University is requesting support for the Center for Biomedical and Health Research Excellence (CBHRE) formerly known as the Institute for Biomedical and Health Disparities Research. The purpose of the CBHRE is to support the conduct of research on two diseases, cancer and cardiovascular, which are leading causes of death in Houston, the state of Texas and the nation. The RCMI program is being reinvented and reinvigorated. The goals of the program are to: 1) upgrade research infrastructure to enhance the university's biomedical research capacity and help promote a research rich environment; 2) enable investigators to become more successful in obtaining competitive extramural support for the conduct of biomedical research, particularly on diseases that disproportionately impact minority populations; and 3) foster vibrant environments conducive to professional development in biomedical sciences. Based on these goals, at the end of five years of RCMI support the CHBRE proposes multiple outcomes including substantial increases in publications citing NIH support; more proposal submissions; more grants awarded; increased number of investigators receiving "mainstream" extramural grant support; and increased number of professional development activities. The CBHRE will have an evaluation component that will be responsible for monitoring the progress of the CBHRE at regular intervals and making recommendations for improvement. The CBHRE will institute a Pilot Program project using a rigorous set of criteria and investigators supported by this program will undergo professional development activities that will help them gain independence within two years of completion of the CBHRE program. The CBHRE and agreed on college and university resources will be leveraged to form new and strengthen collaborations. The CBHRE will be organized into the following activities and/or cores: Administrative Core, Collaborations and Partnerships, Pilot Project Program, Professional Development, Assessment and Evaluation, Environmental Toxicology Research Core, Molecular Biology Research Core and Pharmacology Research Core. Each activity and/or core is designed to support the purpose, goals and objectives of the CBHRE. The core research laboratories will be organized in a manner that will allow investigators access to the state-of-the-art facilities, instrumentatio and service oriented scientific expertise. Multiple investigators will come together to conduct research on cancer and cardiovascular diseases based on discovering common biological, biochemical, genomic, lipidomic, and/or proteomic malfunctions to help understand the mechanistic and clinical relevance of the disease processes.

描述（由申请人提供）：德克萨斯州南部大学要求支持生物医学和健康研究中心（CBHRE），以前称为生物医学和健康差异研究所。 CBHRE的目的是支持有关两种疾病（癌症和心血管疾病）的研究，这是休斯顿，德克萨斯州和国家的死亡原因。 RCMI计划正在重新发明和重新启动。该计划的目标是：1）升级研究基础设施以增强大学的生物医学研究能力并帮助促进研究丰富的环境； 2）使研究人员能够更加成功地获得对生物医学研究的竞争性壁外支持，尤其是在影响少数群体人群不成比例的疾病方面； 3）培养有利于生物医学科学专业发展的充满活力的环境。基于这些目标，在RCMI的五年结束时，CHBRE提出了多种结果，包括以NIH的支持为例，出版物的大幅增长；更多提案提交；授予更多赠款；收到“主流”壁外拨款支持的调查人员数量增加；并增加了专业发展活动的数量。 CBHRE将有一个评估组件，该评估组件将负责定期监视CBHRE的进度并提出改进建议。 CBHRE将使用严格的标准制定一个试点计划项目，该计划支持的调查人员将进行专业发展活动，这将有助于他们在CBHRE计划完成两年内获得独立性。 CBHRE并商定了大学和大学资源，以形成新的和加强合作。 CBHRE将组织为以下活动和/或核心：行政核心，合作和伙伴关系，试点项目计划，专业发展，评估和评估，环境毒理学研究核心，分子生物学研究核心和药理学研究核心。每个活动和/或核心旨在支持CBHRE的目的，目标和目标。核心研究实验室将以允许调查人员进入最先进的设施，仪器和服务于服务的科学专业知识的方式进行组织。多个研究人员将基于发现常见的生物学，生化，基因组，脂肪组和/或蛋白质组学故障，共同进行癌症和心血管疾病的研究，以帮助了解疾病过程的机械和临床相关性。