Characterizing fentanyl outbreaks: Ethnographic and forensic perspectives

芬太尼爆发的特征：人种学和法医学的观点

• 批准号: 9220923
• 负责人: Raminta Daniulaityte
• 金额: $ 22.45万
• 依托单位: WRIGHT STATE UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2016
• 资助国家: 美国
• 起止时间: 2016-06-15 至 2018-05-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9220923
• 关键词: Area; Autopsy; Cessation of life; Characteristics; Charge; Chemistry; Complement; Coroner; Country; County; Crime; Data; Disease Outbreaks; Drug abuse; Drug usage; Epidemic; Epidemiologic Studies; Epidemiology; Ethnography; Fentanyl; Forensic Medicine; Gender; Harm Reduction; Health; Health Knowledge, Attitudes, Practice; Heroin; Intervention; Interview; Knowledge; Laboratories; Link; Methods; Morbidity - disease rate; Motivation; National Institute of Drug Abuse; Ohio; Opioid; Overdose; Pattern; Pharmaceutical Preparations; Pharmacologic Substance; Poisoning; Policies; Population; Price; Public Health; Recording of previous events; Reporting; Research; Research Personnel; Risk; Seizures; Specimen; Stream; Testing; Time; Toxicology; Universities; analog; design; experience; frontier; gender difference; innovation; interdisciplinary collaboration; meetings; mortality; opioid use; overdose death; public health intervention; response; trend

PROJECT SUMMARY Over the past few years, there has been a significant surge in non-pharmaceutical fentanyl (NPF) related unintentional overdose fatalities in multiple states across the U.S. Submitted in response to NIDA PAR- 16-055, Research Area 1 (Responses to sudden and severe emerging drug issues), this time-sensitive R21 application builds on interdisciplinary collaboration between researchers at the Center for Interventions, Treatment and Additions Research, the Department of Chemistry, Montgomery County Coroner's Office/Miami Valley Regional Crime Lab (MCCO/MVRCL) and Public Health-Dayton & Montgomery County. The overall purpose of the proposed study is to characterize NPF outbreaks through the integration of ethnographic/qualitative assessment of active user knowledge and experiences of NPF use, and the results from forensic analyses conducted by the postmortem toxicology and crime laboratories at MCCO/MVRCL. The study will be conducted in the Dayton Area (Montgomery County, Ohio), that has been recognized as a “new frontier” of the U.S. heroin epidemic, and the place of one of the largest NPF outbreaks in the country. The Specific Aims of the study are to: 1) Provide an in-depth understanding of active user knowledge and experiences related to the availability and use of NPF products. 2) Analyze forensic data to characterize toxicological features and epidemiological trends of NPF use. 3) Compare, contrast, and integrate ethnographic and forensic perspectives on NPF outbreaks. The proposed study is significant because it will provide new information about toxicological features of the outbreaks and user knowledge, attitudes and behaviors related to NPF use. The key innovation is the interdisciplinary collaboration to integrate ethnographic and forensic perspectives.

项目摘要 在过去的几年中，这是非药物芬太尼（NPF）的显着激增 美国各地的倍数中相关的意识过量死亡人数，以响应NIDA 16-055，研究区域1（对突然和切断的药物问题的响应），此时间敏感R21 申请基于干预中心研究人员之间的跨学科合作， 治疗和增加研究，蒙哥马利县验尸官办公室/迈阿密化学系 谷地犯罪实验室（MCCO/MVRCL）和蒙哥马利公共健康 支撑研究的目的是表征NPF Outbeaks的整合 民族志/定性评估NPF UFF NPF使用的积极用户知识和经验以及结果 根据MCCO/MVRCL的后毒理学和犯罪实验室进行的法医分析 研究将在代顿地区（俄亥俄州蒙哥马利县）进行，该地区被认为是 美国海洛因流行病的“新边界”，以及该国最大的NPF的位置。 研究的具体目的是：1）对主动用户知识的深入了解和 与NPF产品相关的经验。 NPF使用的毒理学特征和流行病学趋势。 关于NPF爆发的民族志和法医学观点。 提供有关肢体和用户知识，态度和倾向的新信息，以及 与NPF使用有关的行为。 和法医学的观点。