The Administrators of the Tulane Educational Fund dba TUHSC Site Consortium - Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN) Operations and Collaborations Center (UM2 Clinical Tri

杜兰大学教育基金 dba TUHSC 站点联盟的管理者 - HIV/艾滋病干预青少年医学试验网络 (ATN) 运营和合作中心（UM2 临床试验）

• 批准号: 10599564
• 负责人: Sue Ellen Abdalian
• 金额: $ 32.02万
• 依托单位: WESTAT, INC.
• 依托单位国家: 美国
• 财政年份: 2022
• 资助国家: 美国
• 起止时间: 2022-09-22 至 2029-06-30
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/10599564
• 关键词: AIDS/HIV problem; Acquired Immunodeficiency Syndrome; Administrator; Adolescent; Adolescent Medicine; Adolescent Medicine Trials Network; Advertisements; Advocacy; Appointment; Back; Biomedical Research; Clinic; Clinical; Clinical Trials; Collaborations; Communities; Community Outreach; Complex; Dancing; Data Storage and Retrieval; Decision Making; Development; Enrollment; Ensure; Epidemic; Ethics; Event; Feedback; Funding; Gays; Gender; Goals; Government Agencies; HIV; HIV-infected adolescents; HIV/STD; Health; Hepatitis; High Prevalence; Hot Spot; Incidence; Institution; Intervention; Intervention Studies; Investigational Drugs; Laboratories; Leadership; Link; Louisiana; Marketing; Modeling; Monitor; Participant; Patient Recruitments; Persons; Pharmacy facility; Policies; Process; Protocols documentation; Recording of previous events; Research; Research Infrastructure; Research Personnel; Research Project Grants; Risk; Sampling; Secure; Services; Site; Solid; Training; Trust; Universities; Update; Visit; Walking; Work; Youth; artist; base; biobehavior; children of color; clinical research site; design; experience; feasibility research; implementation strategy; innovation; interest; medical schools; meetings; member; operation; outreach; pediatric department; programs; recruit; research study; retention rate; social media

ABSTRACT Tulane University Adolescent Medicine The Tulane University Adolescent Medicine (TUAM) Consortium consists of community members, academic institutions, government agencies, clinics, and community-based organizations (CBOs), that provide services to adolescents at risk for or living with HIV. With a long history of successful collaborations with CBOs, agencies and community members throughout New Orleans, TUAM plans to engage Consortium members with an option to join with site leadership in monthly steering committee meetings to directly link the Consortium to substantive research feasibility and ethics discussions as well as a way of making contributions to the decision- making process. Direct community representation in research planning has been integral to our research conduct. For instance, as part of the consortium, the community advisory board (CAB) consisting of mostly sexual and gender diverse youth of color, provides feedback on research protocols, assists in planning research processes, represents the site in research Network committees, and is active in community outreach planning and participation. Tulane's solid research infrastructure facilitates and encourages the simultaneous implementation of multiple investigational new drug (IND) and biobehavioral protocols without becoming overwhelming. By interest and necessity, TUAM has designed and executed highly adaptive and diverse approaches to recruiting and retaining youth in our research studies. Current recruitment and retention efforts focus on social media-based approaches, but direct outreach in non-traditional settings will increase once again as conditions allow. In New Orleans, creating events that appeal to young people has been an organizing force for our consortium members; a way for collaborators to make their organization and projects known; a way for researchers to be visible as community members; and a way to give back to our participants. As one of the consortia within the Operations and Collaborations Center, the TUAM Consortium plans to: (1) Conduct research projects that have been identified by the Executive Committee and Scientific Leadership Committee; (2) Participate in the development of trials, engaging in ongoing research planning and the development of implementation strategies that build on Consortium strengths; (3) Continue to develop multiple and varied recruitment and retention strategies that resonate with youth; (4) Implement complex ATN research protocols employing highly trained staff and an efficient research infrastructure that engages Consortium sites for research, advocacy and guidance; (5) Provide sufficient laboratory capacity to process samples and effective research pharmacy support; and finally (6) Establish a Consortium leadership model that ensures meaningful and sustained Consortium member engagement.

摘要 杜兰大学青少年医学 杜兰大学青少年医学 (TUAM) 联盟由社区成员、学术界成员组成 为以下人群提供服务的机构、政府机构、诊所和社区组织 (CBO) 有感染艾滋病毒风险或感染艾滋病毒的青少年。与 CBO、机构有着悠久的成功合作历史 以及整个新奥尔良的社区成员，TUAM 计划让联盟成员参与其中 选择与现场领导一起参加每月指导委员会会议，以直接将联盟与 实质性研究可行性和伦理讨论以及为决策做出贡献的方式 制作过程。研究规划中的直接社区代表已成为我们研究的一部分 执行。例如，作为联盟的一部分，社区咨询委员会（CAB）主要由 性和性别多样化的有色人种青年，提供有关研究方案的反馈，协助规划 研究过程，在研究网络委员会中代表该站点，并积极参与社区外展 规划和参与。杜兰大学坚实的研究基础设施促进并鼓励同时进行 实施多项研究性新药 (IND) 和生物行为方案，而无需成为 压倒。出于兴趣和需要，TUAM 设计并执行了高度适应性和多样化的 在我们的研究中招募和留住年轻人的方法。当前的招聘和保留工作 重点关注基于社交媒体的方法，但一旦出现，非传统环境中的直接推广将会增加 在条件允许的情况下再次进行。在新奥尔良，举办吸引年轻人的活动一直是 为我们的联盟成员组织力量；协作者组织和项目的一种方式 已知；一种让研究人员作为社区成员可见的方式；以及回馈参与者的方式。 作为运营与协作中心内的联盟之一，TUAM 联盟计划： (1) 开展执行委员会和科学领导层确定的研究项目 委员会; (2) 参与试验的开发，参与正在进行的研究规划和 制定基于联盟优势的实施战略； （三）持续发展多元 以及与年轻人产生共鸣的各种招聘和保留策略； (4) 实施复杂的ATN研究 雇用训练有素的工作人员和参与联盟站点的高效研究基础设施的协议 用于研究、宣传和指导； (5) 提供足够的实验室能力来处理样品和 有效的研究药学支持；最后（6）建立联盟领导模型，确保 有意义且持续的联盟成员参与。