Shared Resource Group 2: Clinical Shared Resources

共享资源组 2：临床共享资源

基本信息

批准号：
8987511
负责人：
JUDITH Cheryl GASSON
金额：
$ 14.64万
依托单位：
UNIVERSITY OF CALIFORNIA LOS ANGELES
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/8987511
关键词：
Accreditation American Animals Archives Area Basic Science Budgets Cancer Center Cancer Center Support Grant Clinical Clinical Research Computer software Consultations Drug or chemical Tissue Distribution Fees Floor Formalin Freezing Fresh Tissue Funding Grant Health Sciences Histology Human Image Analysis Immunohistochemistry In Situ Hybridization Institutional Review Boards Instruction Jonsson Comprehensive Cancer Center of University of California Los Angeles Laboratories Link Microscopy Online Systems Paraffin Embedding Pathologist Pathology Peer Review Policies Price Procedures Quality Control Research Research Design Research Personnel Research Project Grants Resource Sharing Resources Scanning Services Slide Specimen Surveys Technical Expertise Tissue Procurements Tissue Sample Tissues Training Translational Research United States United States National Institutes of Health Writing animal tissue anticancer research base biobank college cost effective digital high standard human tissue instrumentation interest laser capture microdissection meetings member operation personalized medicine programs quantitative imaging satisfaction virtual web site

项目摘要

The UCLA Translational Pathology Core Laboratory Shared Resource (TPCL SR), a College of American Pathologists (CAP) accredited biobank, provides pathology services essential for basic, translational and clinical cancer research. Remnant human tissue procurement and distribution, histology services (animal and human tissues, frozen and formalin-fixed paraffin embedded specimens, laser capture microdissection), immunohistochemistry and in-situ hybridization services, state-of-the-art digital pathology services (slide scanning and quantitative image analysis) and pathology consultation services (including aid with tissue selection, study design, IRB applications and interpretation of results) are currently available. The instrumentation, staff technical skills, quality and pathology expertise available in the TPCL are expansive and beyond the budget of most labs. In August 2012, TPCL became the fourth biorepository in the United States to be accredited by the College of American Pathologists (CAP). The TPCL Director, Drs. Sarah Dry (ZY) and Co-Director, Jonathan Said (ZY) are both Board Certified, practicing pathologists who conduct basic, translational and clinical research. They have led the successful application for CAP accreditation, supervised renovations of new laboratory space, implemented state-of-the-art biorepository software used by TPCL and written grants that funded the purchase of Definiens image analysis software and a Leica LMD 7000 laser capture microdissection scope. TPCL links researchers with appropriate subspecialty pathologists interested in developing collaborative research projects. Through hands-on instruction and consultation, TPCL endeavors to make researchers comfortable and confident in independently performing image analysis and laser capture microdissection; TPCL can also perform these services for a fee. TPCL usage has remained relatively constant since 2008, reflecting the critical need for our services. From 07/01/2011- 06/30/2012, the TPCL Shared Resource had 254 users, 138 of whom were JCCC members, representing eight Cancer Center Program Areas. Of the 138 member users, 105 had peer-reviewed funding and 33 did not have peer-reviewed funding.

UCLA转化病理学核心实验室共享资源（TPCL SR），美国病理学家学院（CAP）认可的生物库，为基本，转化和临床癌症研究至关重要的病理服务提供了病理学服务。人类组织的采购和分布，组织学服务（动物和人体组织，冻结和福尔马林固定的石蜡嵌入标本，激光捕获微异常），免疫组织化学以及原位杂交服务以及最先进的杂交服务，最先进的数字病理学服务（扫描和定量图像分析）（包括扫描和定量图像分析）以及IRB的应用程序，包括IRB，包括IRB，IRB，包括IRB，包括IRB结果）当前可用。 TPCL提供的仪器，员工技术技能，质量和病理专业知识是广泛的，并且超出了大多数实验室的预算。 2012年8月，TPCL成为美国病理学家（CAP）认可的美国第四次生物座席。 TPCL主任博士。乔纳森（Jonathan）说（ZY）均经过董事会认证，从事基本，转化和临床研究的病理学家。他们领导了成功的CAP认证申请，对新实验室空间进行了监督的翻新，实施了TPCL使用的最先进的生物座谈软件和书面赠款，这些软件资助了购买定质图像分析软件的购买和LEICA LMD 7000 LASER捕获捕获微观回答范围。 TPCL将研究人员与有兴趣开发协作研究项目的适当亚科病理学家联系起来。通过动手的指导和咨询，TPCL努力使研究人员对独立执行图像分析和激光捕获显微解剖的自信； TPCL还可以收费执行这些服务。自2008年以来，TPCL的使用一直保持相对恒定，这反映了对我们服务的关键需求。从07/01/2011- 2012年6月30日开始，TPCL共享资源有254个用户，其中138位是JCCC成员，代表八个癌症中心计划领域。在138位成员用户中，有105位经过同行评审的资金，而33个没有同行评审的资金。