GROW Baby: Improving Maternal Gestational Weight Gain and Infant Growth in the Growing Right Onto Wellness (GROW) Trial

GROW Baby：在 Growing Right Onto Wellness (GROW) 试验中改善母亲妊娠期体重增加和婴儿生长

基本信息

批准号：
9032820
负责人：
William Heerman
金额：
$ 3.56万
依托单位：
VANDERBILT UNIVERSITY
依托单位国家：
美国
项目类别：
财政年份：
2016
资助国家：
美国
起止时间：
2016-01-01 至 2016-04-29
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/9032820
关键词：
Address Affect Age-Months Behavior Behavior Therapy Behavioral trial Birth Body mass index Child Childhood Clinical Communities Comorbidity Complications of Diabetes Mellitus Conceptions Consent Control Groups Cultural Sensitivity Data Development Development Plans Educational process of instructing Enrollment Exposure to Family Fertility Funding Future General Population Gestational Diabetes Growth Guidelines Health Hispanics Hour Hypertension Infant Institute of Medicine (U.S.)Insulin Resistance Intervention Latin American Latina Latino Learning Learning Skill Life Measures Mentors Methods Mothers Obesity Outcome Outcome Measure Parents Perinatal Physical activity Physicians Plant Roots Population Postpartum Period Pregnancy Pregnant Women Preschool Child Public Health Randomized Randomized Controlled Trials Readiness Recommendation Records Research Risk Schools Scientist Testing Training Underserved Population Weight Weight Gain Woman active control aged base behavior change career development clinical practice cohort community center dosage effective intervention feeding gestational weight gain group intervention healthy lifestyle healthy weight high risk improved improved outcome in utero lifestyle intervention multidisciplinary nutrition obesity in children obesity prevention obesity risk pregnancy hypertension pregnant prenatal prevent programs public health relevance skills social cognitive theory theories

项目摘要

DESCRIPTION (provided by applicant): Maternal gestational weight gain (GWG) and rapid infant weight gain are important determinants of a child's lifelong risk of obesity. It is particulrly important to improve these outcomes in the Latino population, where rates of obesity and its associated comorbidities are higher than in the general population. The proposed study (GROW Baby) will test how a behavioral intervention supports healthy maternal GWG (Aim 1) and healthy infant growth (Aim 2). By developing a nested sub-cohort from an ongoing randomized healthy lifestyle trial known as Growing Right Onto Wellness (GROW), GROW Baby will collect new data from both Latina women who become pregnant and their infants born during the study. GROW is a culturally tailored intervention that teaches healthy nutrition and physical activity for both mother and pre-school child (aged 3-5 years). The control condition is a school readiness program. Because intervention-group mothers who become pregnant during the study learn these healthy lifestyle skills prior to or early in pregnancy, the intervention has the potential to support healthy maternal GWG and future infant growth. A committed primary mentor and a multidisciplinary team of co-mentors will oversee the candidate's progression to becoming an independently funded physician scientist with a focus on leveraging healthy behavior changes during pregnancy to prevent and treat maternal and child obesity. The career development plan integrates advanced training in behavioral interventions, community engagement methods, the maternal- child interaction, and targeted approaches to underserved populations. The candidate will gain exposure to senior mentors with expertise in behavioral trials and perinatal nutrition, and will participate in 1) advanced coursework; 2) an ongoing intervention to prevent pediatric obesity; 3) community engagement activities; and 4) a multi-pronged approach applying cultural sensitivity skills to community research with Latino populations. In conducting the proposed research, the candidate will advance the field of maternal-child obesity prevention by understanding how a behavioral intervention implemented before and during pregnancy could support healthy weight for both mother and child.

描述（由适用提供）：孕产妇的妊娠体重增加（GWG）和快速婴儿体重增加是儿童终生肥胖风险的重要决定素。在拉丁裔人口中改善这些结果尤其重要，在拉丁裔人口中，肥胖症及其相关的合并症的比率高于普通人群。拟议的研究（Grow Baby）将测试行为干预如何支持健康的母体GWG（AIM 1）和健康的婴儿生长（AIM 2）。通过从正在进行的随机健康生活方式试验中开发出嵌套的亚果园，称为“生长健康”（成长），成长的婴儿将从孕妇的两位拉丁裔妇女和研究期间出生的婴儿收集新数据。成长是一种文化量身定制的干预措施，为母亲和学龄前儿童（3-5岁）教授健康的营养和体育锻炼。控制条件是学校准备计划。由于研究期间怀孕的干预组母亲在怀孕前或怀孕初期学习这些健康的生活方式技能，因此干预措施具有支持健康的孕产妇GWG和未来婴儿的增长的潜力。一个忠实的主要导师和一个跨学科的联合学团队将监督候选人成为一名独立资助的物理科学家的进步，重点是利用怀孕期间的健康行为改变，以预防和治疗物物物体。职业发展计划将行为干预，社区参与方法，母性互动以及针对服务不足人群的有针对性方法的高级培训整合。候选人将获得具有行为试验和围产期营养专业知识的高级导师的接触，并将参加1）高级课程； 2）正在进行的干预措施，以防止小儿肥胖； 3）社区参与活动； 4）一种多管齐下的方法，将文化敏感技能应用于拉丁裔人群的社区研究。在进行拟议的研究时，候选人将通过了解如何在怀孕之前和期间实施的行为干预来支持母子肥胖的领域。