Summer Training Course in Experimental Aging Research

实验老化研究暑期培训课程

• 批准号: 10560479
• 负责人: HOLLY VAN REMMEN
• 金额: $ 7.49万
• 依托单位: OKLAHOMA MEDICAL RESEARCH FOUNDATION
• 依托单位国家: 美国
• 财政年份: 2018
• 资助国家: 美国
• 起止时间: 2018-05-01 至 2024-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10560479
• 关键词: Age; Aging; Applications Grants; Area; Biological Assay; Biology; Biology of Aging; Biomedical Research; Cardiovascular Diseases; Cities; Committee Members; Course Content; Critiques; DNA Methylation; Development; Disease; Doctor of Philosophy; Doctor' s Degree; Enrollment; Exposure to; Faculty; Fellowship; Foundations; Funding; Funding Opportunities; Gerontology; Grant; Grant Review; Health Sciences; Institution; Interview; Laboratories; Malignant Neoplasms; Medical Research; Methodology; Michigan; Nerve Degeneration; Non-Insulin-Dependent Diabetes Mellitus; Oklahoma; Osteoporosis; Population; Positioning Attribute; Postdoctoral Fellow; Productivity; Proteome; Questionnaires; Research; Research Institute; Research Personnel; Research Project Grants; Research Proposals; Risk Factors; Rotation; Scientific Misconduct; Scientist; Series; Site; Source; Stress; Study Section; Suggestion; System; Systems Biology; Teacher Professional Development; Texas; Training; United States National Institutes of Health; Universities; Washington; age effect; age related; career; design; improved; laboratory experience; lecturer; lectures; member; novel; prevent; programs; success

Funds are requested to continue a series of Summer Training Courses in Experimental Aging Research (STC) that will be held for five days each June from 2019 through 2023. The STC will be directed by Dr. Van Remmen at the Oklahoma Medical Research Foundation (OMRF) and the University of Oklahoma Health Sciences Center (OUHSC). The course site will rotate among three host institutions: OMRF/OUHSC at Oklahoma City, OK, the University of Washington at Seattle, WA and the Buck Institute for Research on Aging at Novato, CA. Similar STCs have been held with great success every summer since 1993. The Course is designed to provide trainees with intensive exposure to the latest research in experimental biogerontology and individualized guidance regarding the development of a research proposal. Each year’s enrollment will be limited to 25 Trainees with most of the Trainees in the formative stage of their careers, i.e., junior faculty in their first four years or postdoctoral fellows in the last year of their fellowship. Each trainee is expected to have at least two years of productive laboratory experience in some aspect of biology beyond the doctoral degree (MD, PhD, or DVM). The five-day program will include the following four activities: (a) overview lectures designed to introduce trainees to the context, latest findings, and unanswered questions in major areas of biogerontology, (b) an opportunity for each trainee to present his or her Specific Aims for a research project that will be critiqued by the Training Faculty, (c) seminars focusing on the NIH system and funding opportunities at the NIA presented by NIA staff and seminars focusing on novel methodological approaches that could be important in studying aging by a faculty member at the host or nearby institution, and (d) after- dinner discussions dealing with what reviewers look for when reviewing grants, how to handle and prevent scientific misconduct in the laboratory, and how to find and interview for a position. Nine scientists will serve as the Steering Committee of the STC and will be responsible for selecting the trainees and making changes in the organization or content of the STC: Drs. Van Remmen, the Director/PI, Richardson, the Co-Director, and Dr. Sonntag who will host the Course at Oklahoma City (OK), Drs. Campisi (Co-PI), Lithgow, and Kapahi who will host the Course at Novato (CA), and Drs. Rabinovitch (Co-PI), Promislow, and Kaeberlein who will host the Course at Seattle (WA). In addition, eight Training Faculty who are leaders in the field of aging and have served on Study Sections related to aging will participate in each STC: 3 faculty from the host institution and 5 faculty from other institutions. Trainees are asked to review each STC and these reviews are considered by the Steering Committee when planning the next STC. The overall rating of the STCs over the past five years by the Trainees has been outstanding. 89% of the former trainees who responded to our poll are still involved in aging research and 59% of the Trainees have been successful in obtaining funding for their research on aging (52% from NIH and 25% from non-federal sources).

需要资金来继续举办一系列实验老化研究夏季培训课程 (STC)，将于 2019 年至 2023 年每年 6 月举行，为期五天。STC 将由 Van 博士指导 Remmen 在俄克拉荷马医学研究基金会 (OMRF) 和俄克拉荷马健康大学 科学中心 (OUHSC) 课程地点将在三个主办机构之间轮换：OMRF/OUHSC，位于 俄克拉荷马州俄克拉荷马城、华盛顿大学西雅图分校和巴克老龄化研究所 自 1993 年以来，每年夏天都会在加利福尼亚州诺瓦托举办类似的 STC。 旨在让学员深入了解实验生物老年学的最新研究和 关于制定研究计划的个性化指导。 仅限25名学员，其中大多数学员处于职业生涯的形成阶段，即初级教师 每位实习生预计将在其前四年或最后一年获得博士后奖学金。 除博士学位外，在生物学某些方面至少有两年富有成效的实验室经验 （MD、PhD 或 DVM）。为期五天的课程将包括以下四项活动：(a) 概述讲座。 旨在向学员介绍主要领域的背景、最新发现和未解答的问题 生物老年学，(b) 每位学员都有机会展示他或她的研究项目的具体目标 将受到培训学院的批评，(c) 重点关注 NIH 系统和资金的研讨会 NIA 工作人员在 NIA 提供的机会以及侧重于新颖方法的研讨会 这对于东道国或附近机构的教职人员研究衰老可能很重要，以及（d）事后- 晚餐讨论涉及评审员在评审拨款时寻找什么、如何处理和预防 实验室中的科学不端行为，以及如何寻找和面试职位。 九名科学家将担任STC指导委员会，负责选择 受训人员以及对 STC 的组织或内容进行更改：Van Remmen 博士，主任/PI， 联合主任理查森 (Richardson) 和将在俄克拉荷马城 (OK) 主持课程的 Sonntag 博士、Campisi 博士 （联合 PI）、Lithgow 和 Kapahi 将在诺瓦托（加利福尼亚州）主持该课程，以及 Rabinovitch 博士（联合 PI）， Promislow 和 Kaeberlein 将在西雅图（华盛顿州）主持该课程。此外，还有八名培训教师。 是老龄化领域的领导者，并曾在与老龄化相关的研究部门任职，将参加每个 STC：要求来自主办机构的 3 名教员和来自其他机构的 5 名教员进行审查。 指导委员会在规划下一个 STC 时会考虑 STC 和这些审查。 过去五年学员对STC的评价为优秀，89%的前学员。 接受我们民意调查的学员仍在参与老龄化研究，并且 59% 的学员已在这方面取得了成功 为他们的老龄化研究获得资金（52% 来自 NIH，25% 来自非联邦来源）。