Mentorship and Research in HIV and Addiction Prevention Among Traumatized Youth

对受创伤青少年进行艾滋病毒和成瘾预防的指导和研究

• 批准号: 9064109
• 负责人: CARLA KMETT DANIELSON
• 金额: $ 18.05万
• 依托单位: MEDICAL UNIVERSITY OF SOUTH CAROLINA
• 依托单位国家: 美国
• 财政年份: 2015
• 资助国家: 美国
• 起止时间: 2015-07-01 至 2020-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/9064109
• 关键词: AIDS prevention; Achievement; Address; Adolescent; Aftercare; Alcohol or Other Drugs use; Area; Award; Behavioral Sciences; Caregivers; Caring; Child Abuse and Neglect; Childhood; Clinical; Clinical Research; Clinical Sciences; Comorbidity; Country; Data; Dedications; Development; Drug usage; Education; Educational Curriculum; Electronics; Evaluation; Evidence based treatment; Exposure to; Faculty; Family; Feasibility Studies; Feeling; Funding; Glean; Goals; HIV; HIV Infections; HIV risk; Health; Health Technology; Human immunodeficiency virus test; Individual; Internships; Interview; Leadership; Learning; Life Experience; Longevity; Mental Depression; Mentors; Mentorship; Methods; Mid-Career Clinical Scientist Award (K24); Modeling; National Institute of Drug Abuse; Oral cavity; Outcome; Population; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Preparation; Prevention; Preventive Intervention; Procedures; Process; Protocols documentation; Psychiatry; Psychologist; Psychology; Public Health; Publications; Randomized; Reaction; Reporting; Research; Research Design; Research Personnel; Research Project Grants; Research Training; Resources; Risk; Risk Behaviors; Risk Factors; Risk Reduction; Role; Science; Scientist; Sex Education; Sexual abuse; Signal Transduction; Specific qualifier value; Stress; Substance Use Disorder; Substance abuse problem; Surveys; Swab; Tablets; Technology; Teenagers; Test Result; Testing; Time; Training; Trauma; United States National Institutes of Health; Update; Violence; Vulnerable Populations; Work; Youth; addiction; base; checkup examination; condoms; cost; design; deter alcohol use; early onset substance use; early-career faculty; effective intervention; evidence base; experience; follow-up; handheld mobile device; high risk; high risk behavior; high risk sexual behavior; innovation; interactive tool; interest; learning engagement; lifetime risk; mHealth; new technology; patient oriented; patient oriented research; physical abuse; pre-doctoral; programs; public health priorities; sex risk; sexual trauma; skills; stem; substance use prevention; tool; training opportunity; traumatic event; usability; web-accessible

 DESCRIPTION (provided by applicant): The purpose of this K24 proposal is to enhance exponentially Dr. Carla Kmett Danielson's mentorship and research program in innovative approaches to risk reduction of HIV infection and addiction among adolescents, with a particular focus on trauma-exposed populations. Dr. Danielson, a clinical psychologist and scientist, is the ideal candidate for this mechanism. She has sustained continuous federal-funding of her patient oriented research (POR) since 2005, which has provided the framework for her mentorship of 19 junior investigators contributing to the science of substance abuse comorbidity with high-risk sexual behaviors and trauma. Her mentees, who have included early career faculty, postdoctoral fellows, and predoctoral psychology interns, have made significant contributions to the HIV prevention, substance abuse, and traumatic stress fields through high-impact publications and independent lines of NIH-funded research. Dr. Danielson's long-standing dedication and achievements in POR mentorship are further evidenced through her leadership roles as PI of an NIH-funded T32 Program dedicated to clinical research training in traumatic stress and its sequelae across the lifespan and as Co-Chair for the Faculty Mentorship Program in MUSC's Department of Psychiatry and Behavioral Sciences (currently ranked 7th in the country for NIH funding). The proposed K24 award will be essential in providing time and resources necessary for the candidate to formalize, expand, and sustain her mentoring program and capacity, further stimulate the research program of her mentees (e.g., through a proposed trainee pilot award program and new training opportunities) and augment her research skills and growing program of research in e- and m-health technologies for traumatized adolescents at risk for HIV infection and addiction. Innovative research proposed by Dr. Danielson under the K24 involves development and evaluation of a dynamic, technology-based prevention tool-kit (electronic HIV-sex Education and Addiction Risk for Traumatized Teens; eHEARTT). The toolkit will enhance the quality, accessibility, and efficacy of HIV- risk and substance use prevention interventions for adolescents receiving trauma-focused treatment. Specific aims of the research are to: 1) Develop the eHEARTT toolkit to support delivery of evidence-based HIV and substance use prevention interventions during the delivery of trauma-focused treatment (TF-CBT); 2) Conduct usability tests of the eHEARTT toolkit with teens, caregivers, and clinicians to guide refinements; and 3) Conduct a randomized controlled feasibility trial with 40 families to evaluate TF-CBT plus eHEARTT in comparison to TF-CBT plus a risk behavior electronic Resource List through a 6-month post-treatment follow- up assessment. These aims harmonize well with Dr. Danielson's proposed mentorship activities and current federally-funded research projects in the areas of HIV prevention, substance use risk reduction, and trauma among teens. The proposed research affords rich training opportunities for her mentees (early career faculty, postdoctoral fellows, and predoctoral psychology interns with an emphasis on trainees from groups under- represented in clinical science) and will invigorate new directions in POR with teens at risk for HIV infection and addiction. The proposed work is directly in line with NIDA priorities and funding announcements that call for research designed to evaluate the application of new technologies for delivering adapted prevention interventions targeting drug and alcohol use and prevention of HIV acquisition.

 描述（由适用提供）：该K24提案的目的是指数增强Carla Kmett Danielson博士的心态和研究计划，以创新的方法来降低青少年的艾滋病毒感染和成瘾，并特别关注受创伤暴露的人群。临床心理学家兼科学家丹尼尔森（Danielson）博士是该机制的理想人选。自2005年以来，她一直持续对以患者为导向的研究（POR）进行联邦资助，这为她的19名初级调查人员的心态提供了框架，这为滥用药物滥用的科学以及高风险的性行为和创伤而做出了贡献。她的受训者包括早期的职业教师，博士后研究员和心理学前的实习生，通过高影响力的出版物和NIH资助的独立行动为预防艾滋病毒的预防，药物滥用和创伤性压力领域做出了重大贡献。 Danielson博士的长期奉献和成就在POR心态方面取得了进一步的证明，她是NIH资助的T32 T32计划的领导角色，该计划致力于整个生命周期的创伤压力及其后遗症的临床研究培训，并作为MUSC的教职员工领导的精神病学会和行为科学领域的教师指导计划（当前是NIH IH IH IH nih IH nishih in nation in n y In nandih In nation in n y In n y Inter Nister）。 The proposed K24 award will be essential in providing time and resources necessary for the candidate to formalize, expand, and sustain her mentaling program and capacity, further stimulate the research program of her mentores (e.g., through a proposed trainee pilot award program and new training opportunities) and augment her research skills and growing program of research in e- and m-health technologies for traumatized adolescents at risk for HIV infection and addiction. Danielson博士在K24下提出的创新研究涉及对基于技术的预防工具KIT的开发和评估（电子HIV-SEX教育和对创伤的青少年的成瘾风险； Eheartt）。该工具包将提高接受以创伤为中心治疗的青少年的HIV风险和药物使用干预措施的质量，可及性和效率。该研究的具体目的是：1）开发Eheartt工具包，以支持以创伤为中心的治疗（TF-CBT）在提供基于证据的HIV和药物使用预防干预措施； 2）与青少年，看护人和临床医生一起对Eheartt工具包进行可用性测试，以指导改进； 3）与TF-CBT相比，通过40个家庭进行了40个家庭的随机控制可行性试验，以评估TF-CBT加上EHEARTT以及风险行为的电子资源清单，通过治疗后的6个月后随访评估。这些目标与丹尼尔森博士的拟议指导活动和当前在艾滋病毒预防，降低药物使用风险的领域和青少年创伤方面的联邦资助的研究项目相协调。拟议的研究为她的Mentores提供了丰富的培训机会（早期职业教师，博士后研究员和托管心理学前实习生，重点是临床科学领域不足的群体的受训者），并将在POR中为POR提供新的方向，因为POR的新指导与HIV感染和成瘾风险的青少年有关。拟议的工作直接符合NIDA的优先事项和资金公告，这些公告呼吁进行研究，旨在评估新技术用于提供针对药物和酒精使用以及预防HIV获取的适应性预防干预措施。