Bioinformatics Shared Resource

生物信息学共享资源

基本信息

批准号：
9097633
负责人：
JAMES K. WILLSON
金额：
$ 13.76万
依托单位：
UT SOUTHWESTERN MEDICAL CENTER
依托单位国家：
美国
项目类别：
财政年份：
资助国家：
美国
起止时间：
至
项目状态：
未结题

来源：
https://reporter.nih.gov/project-details/9097633
关键词：
Applications Grants Arts Bioinformatics Bioinformatics Shared Resource Biostatistics Core Biostatistics Shared Resource Cancer Center Cancer Center Support Grant Cancer Patient Cancer Research Project Cells Clinical Clinical Data Clinical Trials Design Complex Computational Biology Computer Systems Computer software Core Facility Data Data Analyses Data Analytics Data Quality Data Set Databases Development Disease Education Educational workshop Experimental Designs Generations Genetic Genomics Grant High Performance Computing Human Resources Image Analysis Individual Informatics Knowledge Laboratories Lung Malignant Neoplasms Medical Informatics Medical center Mission Modeling Molecular Profiling NCI Center for Cancer Research Nature Online Systems Outcome Paper Peer Review Play Publications Publishing Quality Control Records Research Research Design Research Personnel Research Project Grants Resource Sharing Resources Retrieval Role Science Series Services Solid Survival Analysis Techniques Work abstracting analytical tool anticancer research biomarker discovery cellular imaging computer science computerized data processing data integration data management data sharing member predictive modeling programs software development success tool tumor registry

项目摘要

Harold C. Simmons Cancer Center Bioinformatics Shared Resource (Research Design and Data Analytics Resources) Project Summary/Abstract The Cancer Center Bioinformatics Shared Resource (CCBSR) facility serves as a cutting-edge bioinformatics resource for cancer center members providing bioinformatics research design, data analysis and management support for basic, translational and clinical cancer research in the Simmons Cancer Center. The facility has a team of personnel with expertise in bioinformatics, computer science, imaging analysis, statistical genetics and genomics, database development and data management. The CCBSR works closely with other Cancer Center Shared Resources and institutional core facilities to provide complementary support for the Cancer Center Scientific Programs and Disease-Oriented Teams. As a newly-established Cancer Center Shared Resource, the CCBSR has helped the Cancer Center to achieve its mission in providing high-quality bioinformatics and analysis support for the Cancer Center Scientific Programs and Disease-Oriented Teams. CCBSR personnel have been actively involved in all cancer research programs. Since 2010, the CCBSR has assisted more than 90 Cancer Center Investigators across all scientific programs with high-quality bioinformatics and analysis support, which has led to 60 peer-reviewed scientific publications, including 7 papers published in Nature, Science, Cell and Lancet. In addition to their individual research projects, the core members play critical roles in 7 large active multi-investigator cancer grants, including the UT Lung SPORE. The CCBSR has developed several clinical databases and web-based analysis tools to facilitate the effective storage, retrieval, and analysis of clinical and laboratory data collected by Cancer Center investigators and Cores, which are essential to the success of translational cancer research programs. The CCBSR also organizes a weekly CCBSR research seminar and workshop series on new advances in bioinformatics and computational biology, as well as a CCBSR bi-weekly Tech Talk series focusing on new bioinformatics techniques and software development.

Harold C. Simmons癌症中心生物信息学共享资源（研究设计和数据分析资源）项目摘要/摘要癌症中心生物信息学共享资源（CCBSR）设施可作为尖端的生物信息学提供生物信息学研究设计，数据分析和管理的癌症中心成员资源支持西蒙斯癌症中心的基本，转化和临床癌症研究。该设施有一个具有生物信息学，计算机科学，成像分析，统计遗传学和基因组学，数据库开发和数据管理。 CCBSR与其他癌症中心紧密合作共享资源和机构核心设施，为癌症中心提供补充支持科学计划和面向疾病的团队。作为一个新建立的癌症中心共享资源， CCBSR帮助癌症中心实现了提供高质量生物信息学和分析支持癌症中心科学计划和面向疾病的团队。 CCBSR人员已经积极参与了所有癌症研究计划。自2010年以来，CCBSR的协助超过了 90个具有高质量生物信息学和分析的科学计划的癌症中心研究人员支持，导致了60种经过同行评审的科学出版物，其中包括大自然发表的7篇论文科学，细胞和柳叶刀。除了他们的个人研究项目，核心成员还发挥关键作用在7个大型活性多入侵者癌症疗法中，包括UT肺孢子。 CCBSR已经开发了几种临床数据库和基于Web的分析工具，可促进有效的存储，检索和癌症中心研究人员和核心收集的临床和实验室数据的分析，这是必不可少的转化癌症研究计划的成功。 CCBSR还组织每周CCBSR 有关生物信息学和计算生物学的新进步的研究研讨会和研讨会系列作为CCBSR每两周一次的技术谈话系列，重点是新的生物信息学技术和软件开发。