Cluster A: 1 Genomics Core

集群 A：1 个基因组核心

• 批准号: 9072952
• 负责人: Kevin Knudtson
• 金额: $ 7.37万
• 依托单位: UNIVERSITY OF IOWA
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/9072952
• 关键词: Cancer Center Support Grant; Clinical; Communities; Custom; DNA Microarray Chip; DNA Sequence; Gene Chips; Genomics; Genomics Shared Resource; Genotype; Human Resources; Laboratories; Medical Research; Molecular Biology; Oligonucleotides; Research; Research Personnel; Research Support; Resources; Services; System; Techniques; Technology; Time; Training; Transcript; Update; anticancer research; base; design; exome sequencing; genome sequencing; meetings; member; next generation sequencing; programs

The Genomics Shared Resource (GSR) located in the Eckstein Medical Research Building adjacent to the Holden Cancer Research Laboratories supports research performed by investigators in all HCCC programs. It provides a broad spectrum of services and resources designed to make the state-of-the-art techniques used in DNA sequence and transcript analysis readily available to the UI research and clinical communities. The research-based services and resources include: 1) DNA sequencing and genotyping, 2) custom oligonucleotides, 3) DNA microarrays using both the Affymetrix GeneChip and Illumina BeadArray systems, 4) real-time PCR, 5) molecular biology computing, and 6) genome sequencing using next-generation sequencing (NGS) technologies. The clinically based services include whole exome sequencing (WES). It is the aim of the GSR to provide high quality services to HCCC members with a rapid turnaround, and to support these services with well-trained personnel. GSR also continues to evaluate and update services to remain cutting-edge and provide new services needed, to continue to meet the needs of HCCC investigators. In 2014, the GSR provided services to 124 HCCC members, including members from each of the HCCC programs.

位于埃克斯坦医学研究大楼中的基因组共享资源（GSR） 与Holden Cancer Research Laboratories相邻，支持由 所有HCCC计划的调查人员。它提供了广泛的服务和资源 旨在使DNA序列和转录分析中使用的最新技术 UI研究和临床社区很容易获得。基于研究的服务和 资源包括：1）DNA测序和基因分型，2）自定义寡核苷酸，3）DNA 使用Affymetrix Genechip和Illumina Beadarray系统的微阵列，4）实时 PCR，5）分子生物学计算和6）使用下一代的基因组测序 测序（NGS）技术。基于临床的服务包括整个外显子组测序 （Wes）。 GSR的目的是迅速为HCCC成员提供高质量的服务 周转，并通过训练有素的人员支持这些服务。 GSR也继续 评估和更新服务以保持最先进并提供所需的新服务， 继续满足HCCC调查人员的需求。 2014年，GSR为124 HCCC成员，包括来自每个HCCC计划的成员。