Biostatistics

生物统计学

• 批准号: 8662711
• 负责人: GORDON D GINDER
• 金额: $ 8.19万
• 依托单位: VIRGINIA COMMONWEALTH UNIVERSITY
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/8662711
• 关键词: Biometry; Biostatistics Shared Resource; Cancer Center; Cancer Center Support Grant; Clinical; Clinical Research; Clinical Research Protocols; Clinical Trials; Clinical Trials Data Monitoring Committees; Collaborations; Data; Databases; Development; Development Plans; Effectiveness; Ensure; Experimental Designs; Faculty; Graduate Degree; Individual; Malignant Neoplasms; Mission; Monitor; NCI Center for Cancer Research; Nature; Peer Review Grants; Phase; Play; Procedures; Protocols documentation; Publications; Randomized; Research; Research Design; Research Personnel; Research Project Grants; Research Support; Resource Sharing; Role; Sample Size; Scientist; Services; Staging; Stratification; Universities; Virginia; Work; anticancer research; data management; design; investigator training; member; preclinical study; programs

The Biostatistics Shared Resource (BSR) of the Virginia Commonwealth University (VCU) Massey Cancer Center (MCC) plays a vital role in supporting research at the MCC. Faculty members in the BSR are essential collaborators with members of each of the research programs. The mission of the BSR is to promote excellence in cancer research at the MCC by supporting a biostatistics faculty dedicated to cancer research that provides outstanding biostatistical support and collaboration to MCC members. The defining attribute of the BSR has been to provide biostatistical support to the MCC researchers from the experimental design stage and to continue the support and guidance for sample size requirements and power calculations, study plan development, analysis of the requirement of the statistical design, development of randomization and stratification procedures, interim analyses, analysis of completed results, presentation of research findings, and, ultimately, in the submission of scientific publications. Biostatisticians also participate in the oversight of MCC clinical trials and research protocols through the Protocol Review and Monitoring Committee (PRMC) and additionally support the Data Safety and Monitoring Board (DSMB). The emphasis on the collaborative nature of the work of this shared resource has been a major factor in optimizing the effectiveness of the BSR and it has resulted in gaining support for peer-reviewed grants. In addition to collaboration at all levels in research projects and grant applications, faculty members of the BSR also contribute to the MCC through methodological research that applies directly to programmatic research at the MCC; and in training investigators through seminars and individual sessions, and postdoctoral scientists and clinical fellows through the Clinical Research and Biostatistics graduate degree concentration. Support from the Cancer Center Support Grant (CCSG) is critical to continued provision of high quality statistical input at the earliest phases of the research projects proposed and conducted at the MCC.

弗吉尼亚联邦大学（VCU）梅西癌症中心（MCC）的生物统计学共享资源（BSR）在支持MCC的研究中起着至关重要的作用。 BSR中的教职员工是与每个研究计划的成员的重要合作者。 BSR的任务是通过支持致力于癌症研究的生物统计学教师来促进MCC癌症研究的卓越，该研究为MC CINS提供了出色的生物统计学支持和协作。 The defining attribute of the BSR has been to provide biostatistical support to the MCC researchers from the experimental design stage and to continue the support and guidance for sample size requirements and power calculations, study plan development, analysis of the requirement of the statistical design, development of randomization and stratification procedures, interim analyses, analysis of completed results, presentation of research findings, and, ultimately, in the submission of scientific publications.生物统计学家还通过协议审查和监测委员会（PRMC）参与MCC临床试验和研究方案的监督，并支持数据安全和监测委员会（DSMB）。强调该共享资源工作的协作性质是优化BSR有效性的一个主要因素，并且导致获得了对同行评审的赠款的支持。除了在研究项目和授予应用程序中的各个级别的协作外，BSR的教职员工还通过直接适用于MCC的程序化研究的方法学研究为MCC做出了贡献；在通过研讨会和个体会议以及通过临床研究和生物统计学研究生学位的培训研究人员以及临床研究员的培训研究人员中。癌症中心支持补助金（CCSG）的支持对于在MCC提出和进行的研究项目的最早阶段继续提供高质量的统计投入至关重要。