International Conference on Image Analysis in Three-dimensional Cryo-EM

三维冷冻电镜图像分析国际会议

• 批准号: 8785968
• 负责人: DORIT HANEIN
• 金额: $ 0.5万
• 依托单位: SANFORD BURNHAM PREBYS MEDICAL DISCOVERY INSTITUTE
• 依托单位国家: 美国
• 财政年份: 2014
• 资助国家: 美国
• 起止时间: 2014-09-01 至 2016-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8785968
• 关键词: Advertising; Algorithms; Area; Australia; Biological; Cells; China; Complex; Cryoelectron Microscopy; Data; Development; Educational workshop; Europe; Event; Filtration; Funding; Future; Goals; Image; Image Analysis; International; Japan; Maps; Methodology; Methods; Organelles; Participant; Postdoctoral Fellow; Process; Research Personnel; Resolution; Senior Scientist; Specialist; Students; Surveys; The Sun; Time; Tomogram; United States National Institutes of Health; Universities; Validation; Vision; abstracting; cost; data mining; detector; lectures; meetings; member; method development; movie; particle; posters; programs; public health relevance; symposium; tomography

DESCRIPTION (provided by applicant): The goal of this application is to convene a three-day Workshop on the cutting-edge topic of "Image Analysis in Three-Dimensional Cryo-Electron Microscopy" slated for early spring 2015. This would follow the 1st workshop, which will be held from March 12-15, 2014 at the Granlibakken Conference Center at Lake Tahoe, CA. The goal of the workshop is to bring together specialists in algorithm development to assess the state of the art in image analysis approaches that tackle challenging biological problems and to discuss current limitations and road blocks in the 3D cryo-EM field as currently practiced. The workshop will provide an open forum for developers in this area, both established as well as students/postdocs to consider the detailed algorithms and methodologies in this fast developing field and identify areas in the most need of concerted effort. The central premise of the workshop is that gaining a comprehensive and quantitative understanding of highly sophisticated biological machines, complexes, and organelles of the cell requires the active, timely and coordinated development of complementary image analysis and data mining algorithms and approaches. The program consists of one keynote lecture, five platform sessions with both invited talks (70%), and talks selected from submitted abstracts (30%), as well as two poster sessions. All sessions will focus on interactive discussions with plenty of time for questions. The 2014 meeting will include a special "Vision" talk on the "Past and future of image analysis methods" by David DeRosier, Brandeis University. The talks will survey new method development efforts combined with details on advances within more "traditional" imaging approaches. The current platform sessions for the 2014 meeting are: Map Validation; Single Particle Approaches to Helical Symmetry and 2-D Crystals; Direct Detector Movie Processing; Tomogram Segmentation, Annotation and Filtration; Factors Limiting Resolution in Single Particle Analysis/Tomography; Heterogeneous Data in 2-D and 3-D. Drs. D. Hanein and S. Ludtke serve as Chairs of the meeting and Drs. W. Chiu (US), E. Egelman (US), B. Hankamer (Australia), M. Kikkawa (Japan), D. Mastronarde (US), P. Penczek (US), H. Stahlberg (Europe), F. Sun (China), and N. Volkmann (US) are members of the organizing committee. The Workshop will be extensively advertised and will be as inclusive and diversity-sensitive as the organizers can achieve and the 100-participant limit will allow.

描述（由申请人提供）：本申请的目标是召开一次为期三天的研讨会，主题为“三维冷冻电子显微镜中的图像分析”，定于 2015 年初春举行。这将继第一届研讨会之后研讨会将于 2014 年 3 月 12 日至 15 日在加利福尼亚州太浩湖的 Granlibakken 会议中心举行。研讨会的目标是汇集算法开发专家，评估解决具有挑战性的生物问题的图像分析方法的最新技术，并讨论目前在 3D 冷冻电镜领域实践的局限性和障碍。该研讨会将为该领域的开发人员以及学生/博士后提供一个开放的论坛，以考虑这个快速发展领域的详细算法和方法，并确定最需要共同努力的领域。研讨会的核心前提是，要全面、定量地了解高度复杂的生物机器、复合物和细胞器，需要积极、及时和协调地开发互补的图像分析和数据挖掘算法和方法。该计划包括一场主题演讲、五场平台会议，其中包括受邀演讲（70%）和从提交的摘要中选出的演讲（30%），以及两场海报会议。所有会议都将侧重于互动讨论，并有充足的时间提问。 2014 年会议将包括由布兰迪斯大学 David DeRosier 发表的关于“图像分析方法的过去和未来”的特别“愿景”演讲。会谈将调查新方法的开发工作，并结合更“传统”成像方法的进展细节。 2014 年会议的当前平台会议有： 地图验证；螺旋对称性和二维晶体的单粒子方法；直接探测器电影处理；断层图像分割、注释和过滤；单粒子分析/断层扫描中限制分辨率的因素； 2-D 和 3-D 中的异构数据。博士。 D. Hanein 和 S. Ludtke 担任会议主席，Drs. W. Chiu（美国）、E. Egelman（美国）、B. Hankamer（澳大利亚）、M. Kikkawa（日本）、D. Mastronarde（美国）、P. Penczek（美国）、H. Stahlberg（欧洲）、F Sun（中国）和N. Volkmann（美国）是组委会成员。研讨会将进行广泛的宣传，并将在组织者所能达到的范围内以及 100 名参与者的限制范围内尽可能做到包容性和多样性。