Hydrodynamic forces modulate renal tubular function

水动力调节肾小管功能

• 批准号: 8195554
• 负责人: RAJEEV ROHATGI
• 金额: --
• 依托单位: JAMES J PETERS VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-07-01 至 2013-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8195554
• 关键词: Address; Adenosine; Adult; Affect; Age; Apical; Back; Blood; Blood Pressure; Cells; Cilia; Congestive Heart Failure; Coronary Arteriosclerosis; Development; Diet; Dinoprostone; Disease; Distal; Duct (organ) structure; Epithelial; Epithelial Cells; Epithelium; Equilibrium; Etiology; Excretory function; Extracellular Fluid; Gene Proteins; Genetic Transcription; Homeostasis; Human; Hypertension; In Vitro; Indomethacin; Ingestion; Intercalated Cell; Isotonic Exercise; JUN gene; Kidney; Kidney Diseases; Lead; Link; Lithium; MAPK14 gene; Maintenance; Measurable; Mediating; Mediator of activation protein; Medical; Membrane; Messenger RNA; Metabolism; Mitogen-Activated Protein Kinase Inhibitor; Mitogen-Activated Protein Kinases; Modeling; Molecular; Morbidity - disease rate; Mus; Nephrectomy; Nephrons; Nucleotides; Oryctolagus cuniculus; PTGS2 gene; Pathway interactions; Persons; Phosphotransferases; Physiological; Play; Population; Production; Prostaglandin Antagonists; Prostaglandins; Proteins; Regulation; Research; Research Personnel; Risk; Rodent; Role; Saline; Signal Pathway; Signal Transduction; Sodium Chloride; Stroke; Surface; Testing; Translations; Tubular formation; Urine; Water; absorption; cyclooxygenase 1; cyclooxygenase 2; extracellular; feeding; hypertension treatment; inhibitor/antagonist; mRNA Expression; mortality; mouse PGE synthase 1; novel; paracrine; prevent; prostaglandin E synthase; prostaglandin transporter; response; salt sensitive; shear stress; synthetic enzyme; urinary