Colonic myofibroblast activation of PD-1 pathways in inflammatory bowel diseases

炎症性肠病中结肠肌成纤维细胞 PD-1 通路的激活

• 批准号: 8097751
• 负责人: VICTOR E. REYES
• 金额: $ 39.42万
• 依托单位: UNIVERSITY OF TEXAS MED BR GALVESTON
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-08-02 至 2012-07-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8097751
• 关键词: Accounting; Acute; Address; Affect; Americas; Antigen-Presenting Cells; Area; Blocking Antibodies; Bone Marrow; CD4 Positive T Lymphocytes; Caring; Cells; Chimera organism; Chronic; Coculture Techniques; Colitis; Crohn' s disease; Data; Dendritic Cells; Development; Disease; Epithelium; Equilibrium; Flow Cytometry; Foundations; Functional disorder; Health Care Costs; Helper-Inducer T-Lymphocyte; Homeostasis; Immune; Immune System Diseases; Immune response; Incidence; Inflammation; Inflammatory; Inflammatory Bowel Diseases; Inflammatory disease of the intestine; Interleukin-13; Interleukin-4; Interleukin-5; Intestinal Mucosa; Intestines; Knockout Mice; Lead; Ligands; Link; MHC Class II Genes; Messenger RNA; Modeling; Morbidity - disease rate; Mucous Membrane; Myofibroblast; Oxazolone; Pathogenesis; Pathway interactions; Patients; Peripheral; Phenotype; Physicians; Play; Population; Process; Production; Proteins; Publishing; Regulation; Relative (related person); Reporting; Research Priority; Role; Signal Transduction; T cell response; T-Cell Proliferation; T-Lymphocyte; Testing; Therapeutic; Time; Tissues; Ulcerative Colitis; Visit; Western Blotting; combat; cytokine; gastrointestinal; in vivo; inhibitor/antagonist; insight; large bowel Crohn' s disease; mouse model; novel; overexpression; public health relevance; receptor; response; theories