Aging in Puerto Rico: Longitudinal Follow-Up of the PREHCO Study

波多黎各的老龄化：PREHCO 研究的纵向追踪

基本信息

批准号：
10004551
负责人：
Michael Gabriel Crowe
金额：
$ 61.49万
依托单位：
UNIVERSITY OF ALABAMA AT BIRMINGHAM
依托单位国家：
美国
项目类别：
财政年份：
2019
资助国家：
美国
起止时间：
2019-09-01 至 2024-04-30
项目状态：
已结题

来源：
https://reporter.nih.gov/project-details/10004551
关键词：
Adult Age Aging Archives Area Buffers Characteristics Chronic Chronic Disease Cognitive Control Locus Cross-Cultural Comparison Data Data Collection Disasters Elderly Emotional Stability Event Exposure to Family Funding Funding Opportunities Future Goals Government Hair Health Health and Retirement Study Hispanics Home environment Household Hurricane Hydrocortisone Impaired cognition Injury International Island Life Life Cycle Stages Measures Mental Health Mexican Minority Groups Outcome Participant Performance Personal Satisfaction Physical Function Population Heterogeneity Population Study Proxy Puerto Rican Puerto Rico Quality of life Reporting Resources Risk Saliva Sampling Self Efficacy Sister Social Network Social support Stress Subgroup Survivors Time Translating Visit Vulnerable Populations age group aging population base biopsychosocial cognitive function cognitive testing cohort coping cost effective depressive symptoms design disability enhancing factor epidemiology study experience follow-up genetic analysis hypothalamic-pituitary-adrenal axis informant insight insurance claims migration mortality novel perceived stress population based repository resilience social stressor theories

项目摘要

PROJECT SUMMARY/ABSTRACT In the past decade, Puerto Rico has experienced rapid population aging, financial collapse, mass outward migration of younger people, and then Hurricane Maria. Now is an ideal time to build on the only population- based cohort of older adults in Puerto Rico, unique in having data on health and function prior to these major events. Households across Puerto Rico were visited to identify the first island-wide sample of adults age 60+ years for the Puerto Rican Elderly: Health Conditions (PREHCO) study. A wide range of measures relevant to health and aging, including in-home testing of cognitive and physical function, was collected at baseline (2002/2003) and four years later (2006/2007). We propose to gather two new waves of data related to aging, stress and health in a sample of approximately 1,000 PREHCO survivors. The current project will a) extend PREHCO follow-up to between 16 and 20 years after baseline; b) examine life course predictors of major aging outcomes, namely cognitive impairment, disability, and mortality; c) collect data on hurricane-related stressors and mental health; d) add hair cortisol as a marker of chronic hypothalamic pituitary adrenal (HPA) axis activation; and e) add cognitive and proxy informant measures that align with the Health and Retirement Study (HRS). Our project will enable the following specific aims: Aim 1. Examine longitudinal life course biopsychosocial predictors of cognitive health, cortisol levels, mental health, disability, and mortality 16-20 years after baseline. Aim 2. Examine cross-sectional associations between stressors, resilience-enhancing factors, perceived stress, cortisol, and health, as well as changes in health two years later. Aim 3. Increase utility of PREHCO for cross-cultural comparisons. Puerto Rico is an important part of the U.S. that has largely been omitted from U.S. population-based studies of aging. PREHCO participants are now age 76+ years and given accelerating mortality rates for this age group, our proposal to gather two new time points of follow-up data for PREHCO represents a time-limited opportunity to add to our knowledge about aging, stress, and health in an understudied and potentially vulnerable population.

项目概要/摘要在过去的十年中，波多黎各经历了人口快速老龄化、金融崩溃、大规模外流年轻人的迁移，然后是飓风玛丽亚。现在是在唯一的人口基础上发展的理想时机—— 以波多黎各老年人为基础的队列，在这些专业之前拥有健康和功能数据，这是独一无二的事件。走访了波多黎各各地的家庭，以确定第一个全岛范围内 60 岁以上成年人的样本年波多黎各老年人：健康状况 (PREHCO) 研究。一系列相关措施健康和老龄化，包括认知和身体功能的家庭测试，在基线时收集（2002/2003）和四年后（2006/2007）。我们建议收集两波与衰老相关的新数据，大约 1,000 名 PREHCO 幸存者的样本中的压力和健康状况。当前项目将 a) 延长基线后 16 至 20 年的 PREHCO 随访； b) 检查重大老龄化的生命历程预测因素结果，即认知障碍、残疾和死亡率； c) 收集与飓风相关的压力源的数据和心理健康； d) 添加头发皮质醇作为慢性下丘脑垂体肾上腺 (HPA) 轴的标记激活; e) 添加与健康和退休研究相一致的认知和代理信息提供者测量（HRS）。我们的项目将实现以下具体目标：目标 1. 检查纵向生命历程认知健康、皮质醇水平、心理健康、残疾和死亡率的生物心理社会预测因素 16-20 基线后数年。目标 2. 检查压力源、增强复原力之间的横截面关联因素、感知压力、皮质醇和健康状况，以及两年后健康状况的变化。目标 3. 增加 PREHCO 在跨文化比较中的效用。波多黎各是美国的重要组成部分，在美国基于人口的老龄化研究中被忽略了。 PREHCO 参与者现年 76 岁以上，鉴于这个年龄段的死亡率不断上升，我们建议收集两个新的随访时间点 PREHCO 的数据代表了一个限时的机会，可以增加我们对衰老、压力和健康的了解。未充分研究和潜在弱势群体的健康。