Beacon Sensors and Telerehabilitation to Assess and Improve use of Devices for visual functioning (BeST-AID)

用于评估和改善视觉功能设备使用的信标传感器和远程康复 (BeST-AID)

• 批准号: 10000920
• 负责人: AVA K BITTNER
• 金额: $ 19.38万
• 依托单位: UNIVERSITY OF CALIFORNIA LOS ANGELES
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-01 至 2022-08-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10000920
• 关键词: Blindness; Bluetooth; Characteristics; Clinical; Communities; Custom; Data; Data Collection; Devices; Disease; Emerging Technologies; Enrollment; Equipment; Equipment and supply inventories; Evaluation; Frequencies; Future; Geography; Goals; Hand; Health Services Accessibility; Healthcare; Home environment; Individual; Low Prevalence; Measures; Methods; Monitor; Motion; Office Visits; Outcome; Participant; Patient-Focused Outcomes; Patients; Pattern; Phase III Clinical Trials; Pilot Projects; Procedures; Protocols documentation; Provider; Publications; Publishing; Questionnaires; Randomized; Randomized Controlled Trials; Reading; Research; System; Tablets; Technology; Temperature; Testing; Time; Training; Transportation; Videoconferencing; Vision; Visual; Visual impairment; Work; active control; base; comorbidity; diaries; disability; environmental change; follow-up; improved; innovative technologies; novel; phase III trial; provider-level barriers; recruit; rehabilitation service; sensor; telerehabilitation; time use; vision rehabilitation; volunteer

Project Summary or Abstract The successful application of magnification devices for reading and daily tasks is predicated on their correct use by individuals with low vision (LV). Barriers related to transportation, geography, and/or co- morbidities often limit LV patients’ ability to attend several in-office training sessions as part of low vision rehabilitation (LVR) to optimize visual function with magnification devices. A promising solution is real-time videoconferencing to provide telerehabilitation, involving remotely delivered LVR services by a LVR provider in- office to a patient at home. Telerehabilitation for LV appears to be feasible and acceptable by both patients and LVR providers, yet there are no published outcomes on the potential to improve patients’ visual functioning. Another key issue in LVR is the need for an effective system to continually assess how patients are functioning at home. Ideally this would involve a non-invasive, efficient method to assess when magnifier device abandonment occurs, so that a timely telerehabilitation session can be initiated. Small Bluetooth low energy beacon sensors attached to the handles of magnifiers can collect real-time data regarding minute-to-minute environmental changes, which might serve as an indicator of magnifier use by LV patients at home. Specifically, we propose to assess the potential for telerehabilitation to enhance visual function by providing remotely-delivered LVR training to use magnification devices. Following one in-office training session for new magnification device(s), we aim to determine if there is additional gain in visual functioning by randomizing subjects to telerehabilitation or additional in-office LVR (active control). This will provide estimates of effect size for changes in visual function measures to plan a future larger-scale randomized controlled trial. Participants will be assessed before and after two consecutive periods: (1) one month after a single LVR training session, followed by (2) up to three LVR sessions over a three month period either via telerehabilitation in the participants’ homes or LVR in-office. We will determine which patient characteristics and/or magnification devices are most likely to benefit from telerehabilitation, to be targeted in a future, phase III clinical trial. We will also determine whether data from Bluetooth beacon sensors are valid indicators of hand-held magnifier device usage by LV patients at home. We will deploy Estimote Sticker beacon sensors to subjects enrolled in Aim 1 during the same study period. We anticipate that beacon sensors will measure significantly increased temperature and/or motion when placed on the part of the magnification device held by LV patients while performing daily activities. Beacon sensor data will determine if it is feasible to assess when magnification devices are used, and if the frequency of magnifier use changes following telerehabilitation or in-office LVR. This work will evaluate and refine the procedures for implementing these technologies for LVR, in order to develop future randomized controlled trial protocols. We envision that telerehabilitation and beacon sensors could improve LV patient outcomes by providing follow-up LVR services in a more efficient and timely manner.

项目概要或摘要 放大设备在阅读和日常任务中的成功应用取决于它们的性能 与交通、地理和/或共同障碍有关的低视力 (LV) 人士的正确使用。 作为低视力的一部分，发病率通常限制左心室患者参加几次办公室培训课程的能力 使用放大设备优化视觉功能的康复（LVR）是一种有前景的解决方案。 视频会议提供远程康复，由 LVR 提供商远程提供的 LVR 服务，涉及以下内容： 对在家中的患者进行办公室远程康复似乎是可行的，并且患者和患者都可以接受。 LVR 提供商，但尚未公布有关改善患者视觉功能潜力的结果。 LVR 的另一个关键问题是需要一个有效的系统来持续评估患者的功能情况 理想情况下，这将涉及一种非侵入性、有效的方法来评估何时使用放大镜设备。 发生放弃时，可以及时发起远程康复会话。 连接到放大镜手柄上的信标传感器可以收集有关每分钟的实时数据 环境变化，这可能可以作为左心室患者在家中使用放大镜的指标。 具体来说，我们建议通过以下方式评估远程康复增强视觉功能的潜力： 在一次办公室培训课程之后，提供远程 LVR 培训以使用放大设备。 对于新的放大设备，我们的目标是通过以下方式确定视觉功能是否有额外的增益： 随机分配受试者进行远程康复或额外的办公室 LVR（主动控制）这将提供估计。 视觉功能测量变化的效应大小，以计划未来更大规模的随机对照试验。 参与者将在连续两个周期之前和之后进行评估：(1) 单次 LVR 后一个月 培训课程，然后在三个月内通过远程康复进行 (2) 最多 3 次 LVR 课程 在参与者的家中或在办公室进行 LVR，我们将确定哪些患者特征和/或放大倍数。 设备最有可能受益于远程康复，成为未来 III 期临床试验的目标。 还确定来自蓝牙信标传感器的数据是否是手持放大镜设备的有效指标 我们将为目标 1 中登记的受试者部署 Estimote Sticker 信标传感器。 在同一研究期间，我们预计信标传感器的测量值将显着增加。 当放置在左心室患者持有的放大装置部分上时的温度和/或运动 进行日常活动时，信标传感器数据将确定评估是否可行。 使用放大镜的频率是否在远程康复或办公室 LVR 后发生变化。 这项工作将评估和完善 LVR 实施这些技术的程序，以便 我们设想远程康复和信标传感器开发未来的随机对照试验方案。 可以通过更有效、更及时的方式提供后续 LVR 服务来改善 LV 患者的治疗结果。