SCH: INT: A Virtual Surgery Simulator to Accelerate Medical Training in Cardiovascular Disease

SCH：INT：加速心血管疾病医疗培训的虚拟手术模拟器

• 批准号: 10020975
• 负责人: Alison L Marsden
• 金额: $ 26.53万
• 依托单位: STANFORD UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2019
• 资助国家: 美国
• 起止时间: 2019-09-30 至 2023-06-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/10020975
• 关键词: 3-Dimensional; Anatomic Models; Anatomy; Back; Biomechanics; Blood flow; Cardiac; Cardiology; Cardiovascular Diseases; Cardiovascular system; Case Study; Clinical; Clinical Research; Collaborations; Computational Science; Computer Graphics; Custom; Education; Educational Assessment; Educational Curriculum; Engineering; Ensure; Feedback; Geometry; Goals; Hand; High Performance Computing; Immersion; Intuition; Knowledge acquisition; Learning; Liquid substance; Manuals; Measures; Medical; Medical Students; Medicine; Methodology; Methods; Modeling; Monitor; Operating Rooms; Operative Surgical Procedures; Pathology; Patient-Focused Outcomes; Patients; Physicians; Physics; Physiological; Physiology; Pilot Projects; Postoperative Period; Quick Test for Liver Function; Research; Running; Science; Students; Surgeon; Techniques; Technology; Time; Training; Translating; Universities; Visualization; Work; base; cluster computing; cohort; design; educational atmosphere; experience; experimental study; follow-up; hands-on learning; individual patient; innovation; insight; instructor; medical schools; models and simulation; multidisciplinary; novel; open source; pedagogy; repository; simulation; success; tool; virtual environment; virtual reality; virtual reality environment; virtual reality simulation; virtual surgery

We propose to devise and deploy an integrated virtual surgery simulator to transform training and surgical planning in cardiovascular medicine. By advancing science in graphics, visualization and real-time simulations, and interfacing with virtual reality (VR) technology, we will offer clinical trainees unprecedented depth of insight into cardiac physiology and pathology, accelerating knowledge acquisition and intuition-building that takes years with standard approaches. Equipped with immersive patient-specific visualizations, physicians will 'preview' the effects of surgical techniques on blood flow and physiology, quickly testing many "what-if" scenarios over a large design space. While surgeons currently teach trainees time-honored techniques in a steep and high-stakes learning curve, novel and intuitive VR environments will enable rapid, lower-stakes exploration. Despite advances in cardiovascular patient-specific modeling and simulation, current virtual surgery capabilities are limited to cumbersome by-hand model manipulations and blood flow simulations run on high-performance computing clusters for days at a time. These complexities preclude hands-on use by clinicians and often limit models to a small cohort of anatomic designs. There is, therefore, a pressing need for scientific and technological advances to enable seamless manipulation of anatomic geometry and simulations that can provide real-time feedback. To drive this technology, we aim to overcome critical methodological barriers through the following aims: 1) Develop computer-graphics tools for efficient model manipulation, 2) Integrate reduced-order modeling with visualization to create a real-time interactive experience, and 3) Develop and deploy an interactive VR educational environment for medical students and clinical trainees, complete with case studies and interactive experiences. To quantify impact, we will design and carry out educational assessments measuring the ability of our technology to accelerate learning among medical trainees. To ensure success, we have assembled an expert interdisciplinary team spanning cardiovascular biomechanics, computer graphics, technology in education, and clinical cardiology. Ultimately, the proposed tools will also drive clinical innovation. Since many cardiovascular surgical approaches have changed little in decades, a longer-term goal is to launch clinical studies demonstrating impact on patient outcomes, allowing surgical planning and customization for individual patients.

我们建议设计和部署一个集成的虚拟手术模拟器来改变培训和手术 心血管医学规划。通过推进图形、可视化和实时科学 模拟，并与虚拟现实（VR）技术相结合，我们将为临床实习生提供 对心脏生理学和病理学的前所未有的深入了解，加速知识获取 采用标准方法需要数年时间才能建立直觉。配备沉浸式患者特定 可视化，医生将“预览”手术技术对血流和生理的影响， 在大型设计空间中快速测试许多“假设”场景。虽然外科医生目前正在教学 学员们在陡峭且高风险的学习曲线中学习历史悠久的技术，新颖而直观的 VR 环境将使快速、低风险的探索成为可能。尽管心血管领域取得了进展 针对特定患者的建模和模拟，当前的虚拟手术功能仅限于繁琐 手动模型操作和血流模拟在高性能计算集群上运行 一次几天。这些复杂性妨碍了临床医生的实际使用，并且通常将模型限制在很小的范围内。 解剖学设计队列。因此，迫切需要科学技术进步 实现解剖几何和模拟的无缝操作，可以提供实时 反馈。为了推动这项技术的发展，我们的目标是通过以下方式克服关键的方法障碍： 以下目标：1) 开发计算机图形工具以实现高效的模型操作，2) 集成 通过可视化进行降阶建模，以创建实时交互体验，以及 3) 开发和 为医学生和临床实习生部署交互式 VR 教育环境，完成 案例研究和互动体验。为了量化影响，我们将设计并实施 教育评估衡量我们的技术加速医学学习的能力 实习生。为了确保成功，我们组建了一支跨学科专家团队 心血管生物力学、计算机图形学、教育技术和临床心脏病学。 最终，所提出的工具也将推动临床创新。由于许多心血管外科 几十年来，方法几乎没有改变，长期目标是开展临床研究，证明 对患者结果的影响，允许针对个体患者进行手术规划和定制。