CHARACTERIZATION OF CALIXARENES BY MASS SPECTROMETRY

通过质谱法表征杯芳烃

• 批准号: 8168711
• 负责人: JERRY ATWOOD
• 金额: $ 0.66万
• 依托单位: WASHINGTON UNIVERSITY
• 依托单位国家: 美国
• 财政年份: 2010
• 资助国家: 美国
• 起止时间: 2010-03-10 至 2010-12-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8168711
• 关键词: Calixarenes; Computer Retrieval of Information on Scientific Projects Database; Drug Delivery Systems; Funding; Grant; Institution; Mass Spectrum Analysis; Methods; Polymers; Research; Research Personnel; Resources; Source; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure; United States National Institutes of Health; Work; base; novel; Calixarenes; Computer Retrieval of Information on Scientific Projects Database; Drug Delivery Systems; Funding; Grant; Institution; Mass Spectrum Analysis; Methods; Polymers; Research; Research Personnel; Resources; Source; Spectrometry, Mass, Electrospray Ionization; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Structure; United States National Institutes of Health; Work; base; novel

This subproject is one of many research subprojects utilizing the resources provided by a Center grant funded by NIH/NCRR. The subproject and investigator (PI) may have received primary funding from another NIH source, and thus could be represented in other CRISP entries. The institution listed is for the Center, which is not necessarily the institution for the investigator. Novel calixarenes are being anlayzed by MALDI and ESI mass spectrometry to determine how they agglomerate and if they form particularly stable aggregates based on number and size. This work is also motivated by the increased research into the use of such polymers for drug delivery and the possibility that MS characterization will be required. We aim to develop relaible methods for determining the structure of these polymers.

该副本是利用众多研究子项目之一 由NIH/NCRR资助的中心赠款提供的资源。子弹和 调查员（PI）可能已经从其他NIH来源获得了主要资金， 因此可以在其他清晰的条目中代表。列出的机构是 对于中心，这不一定是调查员的机构。 新型的钙棒烯被Maldi和ESI质谱法对其进行了批评，以确定它们如何结合，并根据数量和大小形成特别稳定的聚集体。 这项工作还引起了人们对使用此类聚合物进行药物输送的研究以及需要MS表征的可能性。 我们旨在开发可靠的方法来确定这些聚合物的结构。