Enhanced Parallel MRI Data Acquisition

增强型并行 MRI 数据采集

• 批准号: 7846822
• 负责人: GARY P ZIENTARA
• 金额: $ 24.49万
• 依托单位: BRIGHAM AND WOMEN'S HOSPITAL
• 依托单位国家: 美国
• 资助国家: 美国
• 起止时间: 至
• 项目状态: 未结题
• 来源: https://reporter.nih.gov/project-details/7846822
• 关键词: Address; Adult; Communication; Computer software; Computers; Coupled; Detection; Development; Diagnosis; Frequencies; Funding; Gel; Goals; Hospitals; Human; Image; Logistics; Magnetic Resonance Imaging; Methods; Modality; Needles; Operative Surgical Procedures; Physicians; Physics; Procedures; Process; Prostate; Public Health; Publishing; RF coil; Research; Research Ethics Committees; Research Personnel; Resolution; Robotics; Sampling; Scanning; Signal Transduction; System; Techniques; Technology; Testing; Three-Dimensional Imaging; Translating; Translations; Work; data acquisition; design; image guided therapy; imaging modality; improved; in vivo; neurosurgery; new technology; prevent; programs; research study; software systems; tool; volunteer

MRI technology for MR-guided therapies and surgeries in the AMIGO suite is unique. While the therapies and surgeries have the need for fast dynamic MRI as in past interventional MRI applications, the MR technology in the AMIGO suite also can benefit from information coming from other imaging modalities. Due to the number of high technology tools readily available to the interventionalist during procedures in the AMIGO suite, a premium is placed on designing the suite's tools' combined capabilities while preventing the technical aspects of use from becoming overwhelming to the interventionalist during a procedure. There must be information integration and ease of use without information overload to fully take advantage of the AMIGO suite. For this reason we propose an implementation-focused project. This project's dynamic MRI research is directed specifically at MRI needs posed by the unique aspects of the AMIGO suite. The project's main objective is to translate the latest 3D dynamic imaging technical advances - specifically published (previously characterized) techniques in Parallel MRI and reduced field-of-view methods - into practical functions on the 3T 16-channel MRI scanner that will be part of our AMIGO suite. The main objective will be accomplished taking advantage of available information from other imaging modalities, and implementing the functionality to address the AMIGO-specific features mentioned above. The imaging technical goal of this research is for high resolution, sub-second 3D imaging individually tailored for the applications of: MR-guided neurosurgery, prostate therapy, and robotic needle / probe placement. The implementations will be tested and evaluated by performing experiments with gel phantoms healthy adult volunteers and in vivo, working with Project 1, while immediate translation into IRB-certified human tests is possible under other funding and a currently active IRB. A major portion of the advanced technology that we will implement will contribute to forming a fully Broadband MRI (BbMRI) scanner in the AMIGO suite. BbMRI refers to a fully integrated scanner hardware and software system for fast, continuous 3D dynamic MR data acquisition in which each system component transmits or receives a broad band of spatial frequency information. This research is relevant to the public health in that it aims to implement improved dynamic imaging methods for continuous 'tv-like1 imaging, using the most advanced physics and computer technology. The Project aims to bring the new methods directly into the hospital so they are available to those in need. The research also aims to make this new technology easily usable for the physicians so they can better excel in their tasks of detection and diagnosis.

Amigo Suite中MRI引导疗法和手术的MRI技术是独一无二的。而疗法 手术需要快速动态MRI，就像过去的介入MRI应用一样，MR Amigo Suite的技术也可以从其他成像方式中受益。到期的 在过程中，介入主义者很容易获得高科技工具的数量 Amigo Suite，在设计套件的工具的组合功能的同时，请放置优质 使用的技术方面从势不可挡到过程中的介入主义者。那里 必须是信息集成和易用性，而无需信息超负荷以充分利用 Amigo Suite。因此，我们建议一个以实施为中心的项目。这个项目的动态MRI 研究专门针对Amigo Suite独特方面所带来的MRI需求。项目 主要目的是翻译最新的3D动态成像技术进步 - 特别发布 （以前是表征）并行MRI和降低的视野方法的技术 - 在3T 16通道MRI扫描仪上的功能将成为我们的Amigo套件的一部分。主要目标是 实现了来自其他成像方式的可用信息，并实施 解决上述Amigo特定功能的功能。成像技术目标 研究是针对高分辨率的高分辨率3D成像，该成像是针对以下应用进行量身定制的：MR引导的 神经外科手术，前列腺疗法和机器人针 /探针放置。实施将进行测试 并通过使用凝胶幻像健康的成人志愿者和体内进行实验来评估 使用项目1，虽然其他资金可以立即转化为IRB认证的人类测试，并且 当前活跃的IRB。我们将实施的高级技术的主要部分将有助于 在Amigo Suite中形成完全宽带MRI（BBMRI）扫描仪。 BBMRI是指完全集成的 扫描仪硬件和软件系统，用于快速，连续的3D动态MR数据获取 系统组件传输或接收广泛的空间频率信息。这项研究是 与公共卫生相关的是，它旨在实施改进的动态成像方法 使用最先进的物理和计算机技术，类似电视的1成像。该项目旨在带来 新方法直接进入医院，因此有需要的人可以使用。这项研究还旨在 使这项新技术很容易适用于医生，以便他们可以更好地擅长检测任务 和诊断。