Exploring strategies to restore function in older Veterans with PTSD.

探索恢复患有创伤后应激障碍 (PTSD) 的老年退伍军人功能的策略。

• 批准号: 8201483
• 负责人: Katherine Shepherd Hall
• 金额: --
• 依托单位: DURHAM VA MEDICAL CENTER
• 依托单位国家: 美国
• 财政年份: 2012
• 资助国家: 美国
• 起止时间: 2012-02-01 至 2014-01-31
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/8201483
• 关键词: Activities of Daily Living; Address; Adherence; Aging; Area; Award; Behavior; Behavior Therapy; Behavioral; Chronic; Clinical; Clinical Trials; Cognitive; Cognitive Therapy; Comorbidity; Counseling; Data; Data Set; Development; Doctor of Philosophy; Education; Elderly; Etiology; Exercise; Focus Groups; Future; Goals; Health; Health Services; Health behavior; Individual; Intervention; Knowledge; Life Style; Measures; Medical center; Mentors; Methods; Modeling; Morbidity - disease rate; Neighborhoods; Older Population; Outcome; Overweight; Paper; Participant; Pathway interactions; Physical Function; Physical activity; Pilot Projects; Population; Post-Traumatic Stress Disorders; Postdoctoral Fellow; Productivity; Psychosocial Factor; Quality of life; Randomized; Research; Research Project Grants; Review Literature; Role; Sampling; Symptoms; Techniques; Time; Training; Veterans; Work; arm; base; behavior change; behavior influence; cohort; compare effectiveness; experience; fitness; functional outcomes; functional restoration; health related quality of life; impaired glucose tolerance; interest; knowledge base; lifestyle intervention; meetings; novel; programs; rehabilitation strategy; response; therapy design

DESCRIPTION (provided by applicant) Exploring strategies to restore function in older Veterans with PTSD. This is a submission for a CDA-1. The candidate for this award is Katherine S. Hall, Ph.D., a postdoctoral fellow at the Geriatric Research, Education, and Clinical Center of the Durham Veterans Affairs Medical Center. Dr. Miriam C. Morey will serve as a primary mentor and Drs. Jean C. Beckham and Hayden B. Bosworth will serve as co-mentors during this award. The overarching goal of this proposal is for the candidate to build a research program in the role of multiple morbidities on behavioral and functional outcomes in older adults; specifically focusing on the added burden of posttraumatic stress disorder (PTSD) in addition to chronic conditions common to older adults. Dr. Hall will explore the added burden of PTSD on adherence and longitudinal trajectories of change in physical activity behavior and functional outcomes. Dr. Hall has identified the variables of interest in an ongoing clinical trial (the Enhancing Fitness Study, Morey PI) and has performed preliminary analysis to explore the impact of PTSD on physical activity and function in a convenience sample of overweight, older Veterans, with impaired glucose tolerance. Dr. Hall's proposed mentored research seeks to extensively characterize these associations in this dataset by examining baseline associations and the effects of PTSD on changes in clinical outcomes over time. Activities under this award include identifying the barriers to physical activity unique to this population and develop cognitive-behavioral strategies to address specific barriers for older adults with multiple morbidities and PTSD. Results from these aims will inform the future development of a pilot study of a randomized, controlled exercise intervention designed to compare the effectiveness of a group-based cognitive-behavioral intervention for increasing adherence to physical activity compared to traditional behavioral interventions in this understudied, but growing, sub-population of older Veterans. Dr. Hall's training plan includes broadening and strengthening her understanding of the etiology and manifestations of PTSD, exploring the potential mechanisms by which PTSD influences physical activity participation, strengthening her background in cognitive-behavioral techniques and applying these principles to physical activity behavior, and statistical handling of longitudinal and between-group analyses. Given the candidate's strong background in physical activity and her experience with research projects in behavioral interventions and functional assessment, a strong knowledge of PTSD as a psychiatric comorbidity and further development of her cognitive-behavioral and statistical knowledge base will enhance her future productivity and potential in this competitive field. The goal is that Dr. Hall will develop a novel and unique area of research that has tremendous potential for developing rehabilitation strategies for maintaining and restoring function in a cohort with multiple morbidities that is aging and likely to impose a high functional burden on VAMC health services.

描述（由申请人提供） 探索恢复患有创伤后应激障碍 (PTSD) 的老年退伍军人功能的策略。 这是 CDA-1 的提交。该奖项的候选人是达勒姆退伍军人事务医疗中心老年研究、教育和临床中心的博士后凯瑟琳·S·霍尔博士。 Miriam C. Morey 博士将担任主要导师，Drs.让·C·贝克汉姆 (Jean C. Beckham) 和海登·B·博斯沃思 (Hayden B. Bosworth) 将担任该奖项的联合导师。 该提案的总体目标是让候选人建立一个研究项目，研究多种发病率对老年人行为和功能结果的影响；除了老年人常见的慢性疾病之外，还特别关注创伤后应激障碍（PTSD）带来的额外负担。 霍尔博士将探讨创伤后应激障碍 (PTSD) 对依从性的额外负担以及体力活动行为和功能结果变化的纵向轨迹。 Hall 博士在一项正在进行的临床试验（增强健康研究，Morey PI）中确定了感兴趣的变量，并进行了初步分析，以探讨 PTSD 对超重老年退伍军人的方便样本的身体活动和功能的影响，其中糖耐量受损。 Hall 博士提出的指导研究旨在通过检查基线关联以及 PTSD 对临床结果随时间变化的影响，广泛描述该数据集中的这些关联。 该奖项的活动包括确定该人群特有的身体活动障碍，并制定认知行为策略，以解决患有多种疾病和创伤后应激障碍的老年人的特定障碍。 这些目标的结果将为未来开展一项随机、受控运动干预的试点研究提供信息，该研究旨在比较基于小组的认知行为干预与传统行为干预相比，在提高体育活动依从性方面的有效性，但老年退伍军人的人口不断增长。 Hall 博士的培训计划包括扩大和加强她对 PTSD 病因和表现的理解，探索 PTSD 影响身体活动参与的潜在机制，加强她在认知行为技术方面的背景，并将这些原则应用于身体活动行为和统计处理纵向和组间分析。 鉴于候选人在体育活动方面的深厚背景以及她在行为干预和功能评估方面的研究项目的经验，对作为一种精神共病的创伤后应激障碍（PTSD）的深入了解以及她的认知行为和统计知识基础的进一步发展将提高她未来的生产力和潜力。这个竞争领域。 Hall 博士的目标是开发一个新颖而独特的研究领域，该领域具有巨大的潜力，可以制定康复策略，以维持和恢复患有多种疾病的人群的功能，这些人群正在老龄化，并可能对 VAMC 卫生服务造成沉重的功能负担。