Multiplex Mass Spectrometric Immunoassays

多重质谱免疫分析

• 批准号: 7824287
• 负责人: DOBRIN NEDELKOV
• 金额: $ 98.31万
• 依托单位: INTRINSIC BIOPROBES, INC.
• 依托单位国家: 美国
• 财政年份: 2008
• 资助国家: 美国
• 起止时间: 2008-09-30 至 2011-03-30
• 项目状态: 已结题
• 来源: https://reporter.nih.gov/project-details/7824287
• 关键词: Multiplex; Mass; Spectrometric; Immunoassays

The objective of the Phase II research project is to continue the development of a quantitative, automated, high throughput, multiplex affinity protein capture technology platform and multiplex mass spectrometric immunoassays for the analysis of more than 50 cancer-related peptides and proteins from bodily fluids. The projects final goal is the assembly of kits containing the multiplex assays, reagents and protocols and the evaluation and optimization of variables affecting product quality, such as packaging and storage conditions.

第二阶段研究项目的目标是继续开发定量、自动化、高通量、多重亲和蛋白捕获技术平台和多重质谱免疫分析，用于分析体液中的 50 多种与癌症相关的肽和蛋白质。该项目的最终目标是组装包含多重测定、试剂和方案的试剂盒，并对影响产品质量的变量（例如包装和储存条件）进行评估和优化。